Pain Studies

Characterization of Lemon Pepper and Black Ginger Extracts and Macroemulsions as Natural Pain Relievers for Spice Stick Balsam Formulation.

Yanti, Harijono C and Lay BW (2023).
Pharmaceuticals (Basel).
PubMed:
36986474

Novel Approach to the Treatment of Neuropathic Pain Using a Combination with Palmitoylethanolamide and Equisetum arvense L. in an In Vitro Study.

This study found that a combination of palmitoylethanolamide and L. can reduce neuropathy and modify pain mechanisms, suggesting a potential alternative treatment option for neuropathic pain.

Ruga S et al (2023).
Int J Mol Sci.
PubMed:
36982577

Rhodojaponin VI indirectly targets Cav2.2 channels via N-ethylmaleimide-sensitive fusion protein to alleviate neuropathic pain.

Rhodojaponin VI is a potential treatment for neuropathic pain. It targets NSF, which regulates Cav2.2 channels and reverses their effect, offering a new class of analgesic products.

Chen K et al (2023).
Acta Pharm Sin B.
PubMed:
36970201

Investigation of the chemical structure and analgesic and anti-inflammatory properties of polysaccharides that constitute the dietary fibers of soursop (Annona muricata) fruit.

This study analyzed the structure and biological activity of dietary fibers from soursop fruits. The soluble fibers promoted pain relief and reduced inflammation in mice. These findings could have potential health benefits.

Lopes Leivas C et al (2023).
Food Res Int.
PubMed:
36914320

Analgesic and Anti-Inflammatory Activities of 80% Methanol Extract and Solvent Fractions of Ehretia cymosa Thonn (Boraginaceae) Leaves in Rodents.

Investigated analgesic and anti-inflammatory effects of methanol extract and fractions on traditional claims of headache, abdominal pain, arthritis, and rheumatism management in Ethiopia.

Ashagrie G, Abebe A and Umer S (2023).
J Exp Pharmacol.
PubMed:
36864852

Effect of Immature Rubus occidentalis on Postoperative Pain in a Rat Model.

Immature rosemary extract (iROE) showed better analgesic and anti-inflammatory effects compared to mature rosemary extract (mROE) in a rat model, potentially through α-adrenergic and opioid receptors.

Choi GJ et al (2023).
Medicina (Kaunas).
PubMed:
36837466

Analgesic and Anti-Inflammatory Effects of 80% Methanol Extract and Solvent Fractions of the Leaves of Vernonia auriculifera Hiern. (Asteraceae).

Crude extract and solvent fractions from the leaves of have potential analgesic and anti-inflammatory properties. Important information for traditional treatment and potential therapeutic applications.

Ashenafi E et al (2023).
J Exp Pharmacol.
PubMed:
36733956

Involvement of the NO/cGMP/K ATP pathway in the antinociceptive effect of rosemary ( Rosmarinus officinalis ) essential oil in mice.

Rosemary essential oil was tested for its pain-relieving properties in mice. The study found that the antinociceptive effect of the oil may be mediated through the NO/cGMP/K ATP pathway.

Hajhashemi V, Salimian M and Hajihashemi O (2023).
Behav Pharmacol.
PubMed:
36730811