Zingiberene, a non-zinc-binding class I HDAC inhibitor: A novel strategy for the management of neuropathic pain.

The researchers explored the potential of a rhizome extract from Zingiber officinalis in inhibiting HDAC1 to reduce neuroinflammation. This could lead to more selective and effective treatments for neurodegenerative diseases.

Borgonetti V et al (2023).

Phytomedicine.

DOI:

10.1016/j.phymed.2023.154670

PubMed:

36681053

Antinociceptive and anxiolytic-like effects of Lavandula angustifolia essential oil on rat models of orofacial pain.

Lavender oil has potential as a safer alternative for pain treatment. It shows analgesic and anxiolytic properties when inhaled, helping to relieve orofacial pain.

Lejeune VBP et al (2023).

J Appl Oral Sci.

DOI:

10.1590/1678-7757-2002-0304

PubMed:

36629536

Effect of carpaine, a major alkaloid from Carica papaya leaves, on dengue virus-2 infection and replication-an in-vitro and in-silico study.

Alagarasu K et al (2023).

Phytother Res.

DOI:

10.1002/ptr.7715

PubMed:

36587936

Isolation and identification of anti-inflammatory and analgesic polysaccharides from Coix seed (Coix lacryma-jobi L.var. Ma-yuen (Roman.) Stapf).

Scientists investigated the analgesic and anti-inflammatory effects of Coix seed, a nutrient-rich food and Chinese medicine. They identified two active compounds that showed significant pain reduction and swelling alleviation. This research provides important insights for potential applications in pain management and inflammation treatment.

Sui Y and Xu D (2022).

Nat Prod Res.

DOI:

10.1080/14786419.2022.2162896

PubMed:

36584288

The effects of Lavandula angustifolia essential oil on analgesic effects and percutaneous absorption of naproxen sodium gel; an in vivo and in vitro study.

Lavandula angustifolia essential oil (LAEO) increased the percutaneous absorption and analgesic effects of naproxen sodium topical gel, suggesting its potential as a permeation-enhancing agent.

Rostamkalaei SS et al (2023).

Clin Exp Pharmacol Physiol.

DOI:

10.1111/1440-1681.13747

PubMed:

36573522

Similarities and differences between Ziqin and Kuqin in anti-inflammatory, analgesic, and antioxidant activities and their core chemical composition based on the zebrafish model and spectrum-effect relationship.

Researchers investigated the differences between two specifications of Scutellaria baicalensis, a traditional Chinese medicine. The Chinese Pharmacopoeia Commission no longer distinguishes between them, but they are still sold separately.

Sun S et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2022.116049

PubMed:

36529251

The combined analgesic, sedative, and anti-gastric cancer mechanisms of Tinospora sagittata var. yunnanensis (S. Y. Hu) H. S. Lo based on integrated ethnopharmacological data.

Tinospora sagittata var. yunnanensis (TSY) is widely used in traditional medicine for pain relief, but its mechanism and active components are unclear.

Wang QQ et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2022.115990

PubMed:

36509262

Interventions for osteoarthritis pain: A systematic review with network meta-analysis of existing Cochrane reviews.

Smedslund G et al (2022).

Osteoarthr Cartil Open.

DOI:

10.1016/j.ocarto.2022.100242

PubMed:

36475286