Phytochemistry Studies

Development of simultaneous quantitative analytical method for three active components of Korean mint (Agastache rugosa (Fisch. & C.A.Mey.) Kuntze) extract in human plasma using ultra-high-performance liquid chromatography-tandem mass spectrometry.

Rinik UR et al (2024).
J Chromatogr B Analyt Technol Biomed Life Sci.
PubMed:
38134516

Combination of Machine Learning and Empirical Computation for the Structural Validation of Trirosaline, a Natural Trimeric Monoterpene Indole Alkaloid from Catharanthus roseus.

Scientists found trirosaline, the first tris-ajmalicine-type monoterpene indole alkaloid and trimeric MIA, from a plant. Its structure was determined using analysis methods and its biosynthetic pathway was proposed. This expands knowledge of alkaloids and biosynthesis. (40 words)

Szwarc S et al (2023).
Org Lett.
PubMed:
38134219

Assessing the In Vitro and In Vivo Effect of Supplementation with a Garlic (Allium sativum) and Oregano (Origanum vulgare) Essential Oil Mixture on Digestibility in West African Sheep.

This study assessed the impact of garlic and oregano essential oil mixture on digestibility in sheep. Results showed that low levels of the mixture improved dry matter digestibility and nutrient intake. The essential oil mixture has the potential to improve fiber digestion and reduce antibiotic use in livestock.

Barreto-Cruz OT et al (2023).
Vet Sci.
PubMed:
38133246

Encapsulation of Olive Leaf Polyphenol-Rich Extract in Polymeric Micelles to Improve Its Intestinal Permeability.

Researchers developed polymeric micelles to enhance the intestinal permeability of an extract with high polyphenol content. The optimized system showed improved permeation of polyphenols in vitro. This could be significant for designing drug delivery systems with enhanced bioavailability.

Bergonzi MC et al (2023).
Nanomaterials (Basel).
PubMed:
38133044

Ethnobotany and phytochemistry of plants used to treat musculoskeletal disorders among Skaw Karen, Thailand.

Karen farmers use medicinal plants to treat musculoskeletal system disorders (MSD), which are common among farmers. Understanding the efficacy of these plants could potentially benefit the health and well-being of farmers worldwide.

Kantasrila R et al (2024).
Pharm Biol.
PubMed:
38131672

Phytochemical analysis, GC-MS profile and determination of antibacterial, antifungal, anti-inflammatory, antioxidant activities of peel and seeds extracts (chloroform and ethyl acetate) of Tamarindus indica L.

Tamarind seeds and peel extracts contained terpenoids, phenolic content, and flavonoids. Chloroform peel extract showed anti-inflammatory and antioxidant activities, while ethyl acetate seed extract inhibited fungal growth. GC-MS analysis revealed beneficial compounds. Seeds extracts were more effective.

Tavanappanavar AN et al (2024).
Saudi J Biol Sci.
PubMed:
38125735

Anti‑adipogenic effect and underlying mechanism of lignan‑enriched nutmeg extract on 3T3‑L1 preadipocytes.

A study investigated the effect of nutmeg extract on fat accumulation in preadipocytes. The extract reduced lipid accumulation by decreasing STAT3 phosphorylation and FAS expression, suggesting potential anti-adipogenic properties.

Perumal NL et al (2023).
Biomed Rep.
PubMed:
38124767