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Ameliorative effect of scopolamine-induced cognitive dysfunction by Fufangmuniziqi formula: The roles of alkaloids, saponins, and flavonoids.

The Fufangmuniziqi formula (FFMN) is a traditional Uyghur medicine in China, composed of 13 herbs. Several of these herbs, including Peganum harmala L., Glycyrrhiza uralensis Fisch., and Nigella glandulifera, have shown potential effects against Alzheimer's disease (AD) by inhibiting acetylcholinesterase (AChE), reducing neuroinflammation, and acting as antioxidants. Despite these promising findings, further research is required to uncover FFMN's precise mechanism of action and to confirm its effectiveness against AD.

Zhao X et al (2023).
J Ethnopharmacol.
PubMed:
37356745