Network pharmacology and multitarget analysis of Nigella sativa in the management of diabetes and obesity: a computational study.

Scientists identified potential compounds from black cumin that can inhibit protein targets and pathways associated with diabetes and obesity. Kaempferol was found to be the best binder for AKT1.

Saleem M et al (2023).

J Biomol Struct Dyn.

DOI:

10.1080/07391102.2023.2222837

PubMed:

37350443

Isolation and characterization of the gene HvFAR1 encoding acyl-CoA reductase from the cer-za.227 mutant of barley (Hordeum vulgare) and analysis of the cuticular barrier functions.

Müller Y et al (2023).

New Phytol.

DOI:

10.1111/nph.19063

PubMed:

37349864

Targeted quantitative analysis of monoterpenoid indole alkaloids in Alstonia scholaris by ultra-high-performance liquid chromatography coupled with quadrupole time of flight mass spectrometry.

Qin Y et al (2023).

J Sep Sci.

DOI:

10.1002/jssc.202200843

PubMed:

37349854

Phytochemical analysis of Origanum majorana L. extract and investigation of its antioxidant, anti-inflammatory and immunomodulatory effects against experimentally induced colitis downregulating Th17 cells.

Taha M et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.116826

PubMed:

37348796

Eugenol relieves the pathological manifestations of Alzheimer's disease in 5×FAD mice.

Summary: Eugenol, a compound found in Syzygium aromaticum, has been found to have therapeutic effects in Alzheimer's disease (AD). AD is a neurodegenerative disease characterized by the buildup of amyloid-β and excessive neuroinflammation, leading to cognitive decline. Eugenol has shown neuroprotective and anti-inflammatory properties, making it a potential treatment option. This research highlights the importance of finding novel ways to combat AD and improve cognitive function.

Jung MJ et al (2023).

Phytomedicine.

DOI:

10.1016/j.phymed.2023.154930

PubMed:

37348246

Facilitated on-line supercritical fluid extraction - supercritical fluid chromatography for nonpolar and polar compounds from milk thistle seeds.

Gros Q et al (2023).

J Chromatogr A.

DOI:

10.1016/j.chroma.2023.464168

PubMed:

37348225

Hepatoprotective effect of Artemisia Argyi essential oil on bisphenol A-induced hepatotoxicity via inhibition of ferroptosis in mice.

Artemisia argyi essential oil (AAEO) protects the liver from the toxic effects of BPA by reducing liver enzyme levels, improving liver health, and preventing ferroptosis.

Cui W et al (2023).

Environ Toxicol.

DOI:

10.1002/tox.23877

PubMed:

37347548

Whole-Genome Sequence of Paenibacillus marchantiae Isolated from the Liverwort Marchantia polymorpha subsp. ruderalis Ecotype BoGa.

Meierhenrich A et al (2023).

Microbiol Resour Announc.

DOI:

10.1128/mra.00354-23

PubMed:

37347158