Discovery of anti-SARS-CoV-2 secondary metabolites from the heartwood of Pterocarpus santalinus using multi-informative molecular networking.

A study found that a pigment-depleted extract from the heartwood of L. f. contains compounds with potential anti-SARS-CoV-2 activity. This discovery emphasizes the significance of advanced analytical methods in identifying treatments and understanding natural compounds' therapeutic abilities.

Wasilewicz A et al (2023).

Front Mol Biosci.

DOI:

10.3389/fmolb.2023.1202394

PubMed:

37347040

Promising roles of Zingiber officinale roscoe, Curcuma longa L., and Momordica charantia L. as immunity modulators against COVID-19: A bibliometric analysis.

Study examines therapeutic potential of antioxidant, anti-inflammatory, immune-stimulating plants against SARS-CoV-2. India leads research, proposes herbal blend for COVID-19 treatment and prevention.

Sheikh HI et al (2023).

J Agric Food Res.

DOI:

10.1016/j.jafr.2023.100680

PubMed:

37346755

Scoparone inhibits breast cancer cell viability through the NF‑κB signaling pathway.

Wu X et al (2023).

Exp Ther Med.

DOI:

10.3892/etm.2023.12027

PubMed:

37346408

Diospyros lotus leaf extract and its main component myricitrin regulate pruritus through the inhibition of astrocyte activation.

The study focuses on the potential use of the plant extract and its main component, myricetin, in alleviating histamine-independent pruritus (itching). By evaluating the effects on signal transducer and activator of transcription 3 (STAT3) activation, glial fibrillary acidic protein (GFAP) expression, and lipocalin-2 (LCN2) production in astrocytes, as well as scratching behavior, mast cell infiltration, and IL-6 levels in mice, the researchers found that the extract and myricetin inhibited STAT3 activation, GFAP expression, and LCN2 release in astrocytes. Moreover, they also ameliorated scratching behavior and other allergic responses in mice. These findings suggest that the plant extract and myricetin could be potential therapeutic agents for the treatment of pruritus.

Shin JY et al (2023).

Exp Ther Med.

DOI:

10.3892/etm.2023.12022

PubMed:

37346401

The complete chloroplast genome sequence of Chrysojasminum subhumile and its phylogenetic position within Oleaceae.

Ling X, Liao R and Zhu X (2023).

Mitochondrial DNA B Resour.

DOI:

10.1080/23802359.2023.2224460

PubMed:

37346171

Genome-wide association analysis provides insights into the genetic basis of photosynthetic responses to low-temperature stress in spring barley.

Elakhdar A et al (2023).

Front Plant Sci.

DOI:

10.3389/fpls.2023.1159016

PubMed:

37346141

Phylogenomic analysis, cryptic species discovery, and DNA barcoding of the genus Cibotium in China based on plastome data.

Jiang RH et al (2023).

Front Plant Sci.

DOI:

10.3389/fpls.2023.1183653

PubMed:

37346120

Optimizing the Production of Antioxidant and Antibacterial Alkaloids from Macleaya cordata by Subcritical Water Extraction Technology.

Zhang J et al (2023).

Chem Biodivers.

DOI:

10.1002/cbdv.202300048

PubMed:

37345892