Inhibition of oxidative stress and advanced glycation end-product formation in purified BSA/glucose glycation system by polyphenol extracts of selected nuts from Pakistan.

Atta A et al (2023).

Food Sci Nutr.

DOI:

10.1002/fsn3.3331

PubMed:

37324872

Antioxidant and antimicrobial activity of two Costa Rican cultivars of ber (Ziziphus mauritiana): An underexploited crop in the American tropic.

Cubero-Román E et al (2023).

Food Sci Nutr.

DOI:

10.1002/fsn3.3317

PubMed:

37324859

Functional, antioxidant, and sensory properties of mixed-fruit (pitaya, watermelon, and mint) and pitaya wines.

Hu TM et al (2023).

Food Sci Nutr.

DOI:

10.1002/fsn3.3334

PubMed:

37324831

Genome-wide identification and expression profiling of B3 transcription factor genes in Populus alba × Populus glandulosa.

Wei M et al (2023).

Front Plant Sci.

DOI:

10.3389/fpls.2023.1193065

PubMed:

37324718

Domestication, breeding, omics research, and important genes of Zizania latifolia and Zizania palustris.

Xie YN et al (2023).

Front Plant Sci.

DOI:

10.3389/fpls.2023.1183739

PubMed:

37324716

Re-sequencing and morphological data revealed the genetics of stone shell and kernel traits in apricot.

Zhang Q et al (2023).

Front Plant Sci.

DOI:

10.3389/fpls.2023.1196754

PubMed:

37324711

Investigating the modulatory effects of Moringa oleifera on the gut microbiota of chicken model through metagenomic approach.

Soundararajan S et al (2023).

Front Vet Sci.

DOI:

10.3389/fvets.2023.1153769

PubMed:

37323848

Molecular docking appraisal of Dysphania ambrosioides phytochemicals as potential inhibitor of a key triple-negative breast cancer driver gene.

Triple-negative breast cancer (TNBC) is an aggressive form of breast cancer that lacks response to hormone therapy. There is a need for targeted molecular therapy for TNBC. The PI3K/AKT/mTOR signaling pathway plays a crucial role in TNBC, and AKT is a promising therapeutic target. In this study, researchers screened 25 compounds from a traditional herbal recipe for their anticancer properties. They found two compounds, cynaroside and epicatechin gallate, to be potent inhibitors of AKT 1 and 2 isoforms. These compounds demonstrate drug-like properties and show structural stability. Computational modeling suggests they could be effective drug candidates for TNBC, but further research is needed for clinical application.

Anifowose LO et al (2023).

In Silico Pharmacol.

DOI:

10.1007/s40203-023-00152-6

PubMed:

37323538