Ultrasound-Assisted Extraction of Verbascoside from Clerodendrum glandulosum Leaves for Analysis of Antioxidant and Antidiabetic Activities.
- Khound P et al (2023).
- ACS Omega.
- PubMed:
- 37323385
Curcumin, extracted from turmeric, has long been used in traditional medicine for its medicinal properties. A protein called SVCT2, responsible for transporting Vitamin C into cells, is involved in tumor progression and metastasis. However, the impact of curcumin on SVCT2 remains unknown. In our study, we found that curcumin reduced the expression of SVCT2 in cancer cells with wild-type p53. This resulted in decreased cancer cell growth and migration, as well as reduced MMP2 activity. Our findings provide new insights into curcumin's anticancer effects and offer potential therapeutic strategies for treating metastatic migration.
Researchers have found that a specific polysaccharide, called α-1,6-galactan, derived from the chanterelle mushroom, can improve memory and reduce the harmful buildup of amyloid plaques in Alzheimer's disease (AD) mice. By reducing the molecular weight of the polysaccharide, its absorption and solubility are improved, leading to better results. The study suggests that these effects are due to the polysaccharide's anti-neuroinflammatory properties. This research may contribute to the development of new treatments for AD using natural polysaccharides.