Nutritional characterization and antioxidant properties of various edible portions of Cucurbita maxima: A potential source of nutraceuticals.

Jahan F et al (2023).

Heliyon.

DOI:

10.1016/j.heliyon.2023.e16628

PubMed:

37303524

HPTLC Stability Indicating Analytical Method of Andrographolide and 5-fluorouracil with Network Pharmacology Analysis against Cancer.

Combining herbal drugs with chemotherapeutic drugs shows promise in reducing side effects and improving efficacy. One such herbal compound, Andrographolide, has been found to have anti-cancer properties. Researchers have developed a combination nanoformulation with Andrographolide and the chemotherapeutic drug 5-fluorouracil to enhance oral absorption and bioavailability. This research highlights the potential for more effective and tolerable cancer treatments.

Malik Z et al (2023).

Comb Chem High Throughput Screen.

DOI:

10.2174/1386207326666230609104038

PubMed:

37303181

Genome-wide characterization of the VQ genes in Triticeae and their functionalization driven by polyploidization and gene duplication events in wheat.

Ma J et al (2023).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2023.125264

PubMed:

37302635

Activation of bitter taste receptors by saponins and alkaloids identified in faba beans (Vicia faba L. minor).

Karolkowski A et al (2023).

Food Chem.

DOI:

10.1016/j.foodchem.2023.136548

PubMed:

37302309

Lessons learned from metabolic engineering in hairy roots: Transcriptome and metabolic profile changes caused by Rhizobium-mediated plant transformation in Cucurbitaceae species.

Almeida A et al (2023).

Plant Physiol Biochem.

DOI:

10.1016/j.plaphy.2023.107797

PubMed:

37302255

Antidepressant evaluation of Andrographis paniculata Nees extract and andrographolide in chronic unpredictable stress zebrafish model.

Researchers investigated the anti-depressive properties of Andrographis paniculata extract and andrographolide in a zebrafish model of chronic unpredictable stress. Both compounds showed a reduction in freezing duration compared to the stressed, untreated group, and andrographolide also decreased cortisol levels and increased activity. The study confirms the potential of zebrafish as a model for researching antidepressant drugs and suggests further investigation of andrographolide's cellular and molecular effects.

Aldurrah Z et al (2023).

Comp Biochem Physiol C Toxicol Pharmacol.

DOI:

10.1016/j.cbpc.2023.109678

PubMed:

37301417

Dammarane-type saponins from Gynostemma pentaphyllum and their anti-aging activities via up-regulating mitochondria related proteins.

Liang HZ et al (2023).

Phytochemistry.

DOI:

10.1016/j.phytochem.2023.113744

PubMed:

37301356

Chitosan-pullulan films enriched with Artemisia annua essential oil: Characterization and application in grape preservation.

Chen W et al (2023).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2023.125216

PubMed:

37301341