Salvianolic acids from Salvia miltiorrhiza Bunge and their anti-inflammatory effects through the activation of α7nAchR signaling.
- Zou LF et al (2023).
- J Ethnopharmacol.
- PubMed:
- 37331452
Coriander extract improved diabetic gonadal dysfunctions in female rats and their offspring by mitigating histological, immunohistochemical, biochemical, and apoptotic alterations.
Terpenoid compounds found in Cannabis sativa plants, specifically the delta-9-tetrahydrocannabinol (THC) and cannabidiol (CBD), have already shown central and peripheral activities in treating brain diseases like Alzheimer's and multiple sclerosis. In this study, we examined the effects of CBD- and THC-rich oils on aluminum (Al)-induced toxicity using the zebrafish model. We measured behavioral biomarkers and biochemical markers related to neurotoxicity. The results showed that the oils increased the activity of the enzyme acetylcholinesterase, which helped the cholinergic nervous system combat Al toxicity. These findings suggest that CBD- and THC-based oils may protect against neurological and antioxidant impairment caused by Al intoxications, and could have potential in preventing related conditions.
Chios Mastiha Essential Oil (CMEO) improved blood lipid profile, blood pressure, weight, body fat, and quality of life in individuals with abdominal obesity and metabolic abnormalities. It may have anti-obesity effects through inflammation and antioxidant modulation.