High accumulation of the Man(5)GlcNAc(2) structure by combining N-acetylglucosaminyltransferase I gene suppression and mannosidase I gene overexpression in Nicotiana tabacum SR1.
- Sato K et al (2023).
- J Biosci Bioeng.
- PubMed:
- 37311682
Withaferin-A (WA), found in Ashwagandha, has anti-inflammatory properties. It was tested in a mouse model of acute graft versus host disease (aGvHD) after stem cell transplants. The mice given WA had fewer symptoms and better survival than the control group. They also had better survival than those given the standard treatment. WA reduced inflammatory cytokines and increased anti-inflammatory cytokines. It also protected organs from damage. WA could be a useful treatment for aGvHD and should be studied in clinical trials.
In this study, researchers examined the acute effects of a beverage containing cashew and Brazil nuts on oxidative stress, lipemia, and blood pressure in women with cardiometabolic risk. They found that the beverage led to a significant reduction in postprandial malondialdehyde levels, suggesting potential cardiovascular benefits.