MdMPK3 and MdMPK6 fine-tune MdWRKY17-mediated transcriptional activation of the melatonin biosynthesis gene MdASMT7.
- Song H et al (2023).
- J Pineal Res.
- DOI:
- 10.1111/jpi.12891
- PubMed:
- 37282752
Researchers used a chronic epileptic mouse model to better understand epilepsy and search for new anti-epileptic drugs. They repeatedly delivered sub-convulsive stimuli, causing massive convulsions. They also looked at the effects of Morinda citrifolia (Noni) extracts, which have been used in Ayurvedic medicine to treat various ailments and were recently shown to help protect mice from memory loss caused by amyloid beta. This study could lead to new treatments for epilepsy and other neurological conditions.
Scientists reviewed the potential use of a medicinal plant known as in treating cardiovascular diseases. Previous studies suggest that and its active components have protective effects, but more research is needed to validate their use and explore potential side effects.