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The potential of lemon balm (Melissa officinalis L.) essential oil as an anti-anxiety agent - is the citronellal the activity carrier?

The hunt for anxiolytic drugs has been challenging, leading to increased use of ethnomedicines like Melissa officinalis L. (lemon balm) for self-managing anxiety symptoms. The herb has been traditionally used for its calming effects and has shown efficacy in clinical studies. Its active principles, including rosmarinic acid and flavonoids, modulate neurotransmitter systems implicated in anxiety disorders. This highlights the potential of natural products as alternative therapies.

Stojanović NM et al (2023).
J Ethnopharmacol.
PubMed:
37207879