Flavonoids of Chromolaena odorata (L.) R.M.King & H.Rob. as potential leads for treatment against tuberculosis.
- Omokhua-Uyi AG et al (2023).
- S Afr J Bot.
- PubMed:
- 37206481
This study looked at the biological potential and phytochemicals of three Methi species. They performed anti-acetylcholinesterase and anti-lipase assays and found that one species had the highest inhibition percentage and cytotoxic potential against certain cell lines. They also identified several bioactive therapeutic compounds that could be useful in the pharmaceutical industry.
Blume, a traditional medicinal plant, has been used to treat neurological diseases due to its neuroprotective effect. To study its effect on cognition impaired by simulated weightlessness, mice subjected to hindlimb unloading were given fresh Blume orally. Behavioral tests showed significant improvement in short- and long-term spatial memory, while biochemical tests demonstrated a reduction in oxidative stress levels and maintenance of pro-inflammatory and anti-inflammatory factor balance in the hippocampus. Fresh Blume also corrected abnormal changes in synapse- and glutamate neurotransmitter-related protein. These results suggest a potential application of fresh Blume in the prevention of cognitive impairment in space.
This study will explore if inorganic nitrate and breakfast can improve working memory, cerebral blood flow, arterial stiffness, and psychological outcomes in Swedish adolescents.
Mimosa pudica plants and rat heart cells show distinct electrical responses to different stimuli. Cooling affects specific branches, while heat affects the whole plant. Mechanical cutting activates the plant with a time delay, suggesting its role in propagating harmful stimuli.
In this study, researchers investigated the potential medicinal properties of flavonoids and volatile components from the peel of (L.) Osbeck, commonly known as the sweet orange. Their findings suggest that flavonoids have a higher probability of being effective against certain anti-cancer drug targets compared to volatile components. The compound chlorogenic acid showed the strongest binding affinity to important anti-cancer targets, indicating its therapeutic potential. These results highlight the importance of flavonoids from sweet oranges and call for further research to optimize their use in medical treatments.