Comparison of five DNA extraction methods in three medicinal plants: Peganum harmala L., Tamarix ramosissima Ledeb., and Potentilla reptans L.
- Salehi Z et al (2023).
- Mol Biol Res Commun.
- PubMed:
- 37201033
Summary: This study investigated the antiproliferative activity of khasianine on pancreatic cancer cells. Khasianine, extracted from fruits, inhibited the growth of human and rat pancreatic cancer cell lines. The researchers identified sugar-sensitive proteins and found that khasianine downregulated lactose-sensitive proteins the most. Rhamnose-sensitive proteins were upregulated in pancreatic cancer patients and a rat model. The study also identified the Ras homolog family member A (RhoA) as a key signaling pathway. Overall, this research suggests that khasianine has potential as a treatment for pancreatic cancer.
Bilobalide from Ginkgo biloba leaves has cardioprotective effects in myocardial infarction by reducing cardiomyocyte apoptosis and myocardial fibrosis via the inactivation of JNK/p38 MAPK signaling pathways. It may be an effective treatment.