All Studies

Isolation and Identification of Flavanone Derivative Eriodictyol from the Methanol Extract of Afzelia africana Bark and Its Antimicrobial and Antioxidant Activities.

Vigbedor BY, Osei Akoto C and Neglo D (2023).
Evid Based Complement Alternat Med.
PubMed:
37200890

Khasianine Affects the Expression of Sugar-Sensitive Proteins in Pancreatic Cancer Cells, Which Are Altered in Data from the Rat Model and Patients.

Summary: This study investigated the antiproliferative activity of khasianine on pancreatic cancer cells. Khasianine, extracted from fruits, inhibited the growth of human and rat pancreatic cancer cell lines. The researchers identified sugar-sensitive proteins and found that khasianine downregulated lactose-sensitive proteins the most. Rhamnose-sensitive proteins were upregulated in pancreatic cancer patients and a rat model. The study also identified the Ras homolog family member A (RhoA) as a key signaling pathway. Overall, this research suggests that khasianine has potential as a treatment for pancreatic cancer.

Sagini MN et al (2023).
ACS Pharmacol Transl Sci.
PubMed:
37200805

Bilobalide Prevents Apoptosis and Improves Cardiac Function in Myocardial Infarction.

Bilobalide from Ginkgo biloba leaves has cardioprotective effects in myocardial infarction by reducing cardiomyocyte apoptosis and myocardial fibrosis via the inactivation of JNK/p38 MAPK signaling pathways. It may be an effective treatment.

Song W et al (2023).
Mol Biotechnol.
PubMed:
37199885