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The Zhuidu Formula (ZDF) contains triptolide, cinobufagin, and paclitaxel, derived from natural sources. Studies have shown that these compounds have anti-tumor properties by affecting DNA synthesis, promoting tumor cell death, and disrupting tubulin balance. However, their role in inhibiting triple-negative breast cancer (TNBC) metastasis remains unclear. Understanding this mechanism could lead to new treatments for TNBC.
Tetrastigma Hemsleyanum Diels et Gilg (SYQ) is a traditional Chinese medicine used for anti-tumor treatment. Researchers have found that the polysaccharide component of SYQ has antioxidant and anti-inflammatory properties. However, its impact on antitumor activity and the underlying mechanism are not yet well understood. This research aims to uncover the potential benefits of SYQ-PA in fighting tumors, shedding light on its significance for future cancer treatments.