All Studies

An In Vitro and In Vivo Assessment of Antitumor Activity of Extracts Derived from Three Well-Known Plant Species.

This study evaluated the antitumor activity of extracts from three plant species: L., L., and L. Using HPLC-MS analysis, the phytochemical profile of the extracts was determined. In vitro screening revealed that L. extracts had the strongest anticancer and antioxidant effects. In vivo assessment using a mouse model showed that administration of L. and green coffee bean extracts reduced ascites cell viability and oxidative stress in tumor samples. Combining chemotherapy with L. or L. extracts induced lipid peroxidation in tumor cells, decreasing tumor viability. These findings suggest that L. extract, especially, has potential as an anticancer agent when used in combination with chemotherapy.

Gligor O et al (2023).
Plants (Basel).
PubMed:
37176897

In Vitro and In Vivo Therapeutic Potential of 6,6'-Dihydroxythiobinupharidine (DTBN) from Nuphar lutea on Cells and K18-hACE2 Mice Infected with SARS-CoV-2.

Researchers found that the alkaloid mixture DTBN extracted from nuphar luteum is effective against COVID-19 in vitro and in vivo. DTBN inhibits SARS-CoV-2 production, reduces viral load in lungs, and exhibits anti-inflammatory properties, making it a promising candidate against the virus. Further studies are needed to optimize its use.

Weiss S et al (2023).
Int J Mol Sci.
PubMed:
37176034