Identification, Characterization, and Cytological Analysis of Several Unexpected Hybrids Derived from Reciprocal Crosses between Raphanobrassica and Its Diploid Parents.
- Yu J et al (2023).
- Plants (Basel).
- PubMed:
- 37176933
This study evaluated the antitumor activity of extracts from three plant species: L., L., and L. Using HPLC-MS analysis, the phytochemical profile of the extracts was determined. In vitro screening revealed that L. extracts had the strongest anticancer and antioxidant effects. In vivo assessment using a mouse model showed that administration of L. and green coffee bean extracts reduced ascites cell viability and oxidative stress in tumor samples. Combining chemotherapy with L. or L. extracts induced lipid peroxidation in tumor cells, decreasing tumor viability. These findings suggest that L. extract, especially, has potential as an anticancer agent when used in combination with chemotherapy.
Researchers found that the alkaloid mixture DTBN extracted from nuphar luteum is effective against COVID-19 in vitro and in vivo. DTBN inhibits SARS-CoV-2 production, reduces viral load in lungs, and exhibits anti-inflammatory properties, making it a promising candidate against the virus. Further studies are needed to optimize its use.