All Studies

Corrigendum to "Disclosing targets and pharmacological mechanisms of total bioflavonoids extracted from Selaginella doederleinii against non-small cell lung cancer by combination of network pharmacology and proteomics" [J. Ethnopharmacol. 286 (2022) 114836].

Xu D et al (2023).
J Ethnopharmacol.
PubMed:
36997372

Polygonum sibiricum polysaccharides exert the antidepressant-like effects in chronic unpredictable mild stress-induced depressive mice by modulating microbiota-gut-brain axis.

Researchers studied the effects of Polygonum sibiricum polysaccharides (PSP), a component of a traditional Chinese medicine, on mice with depression caused by chronic mild stress. The study aimed to determine if PSP worked through the microbiota-gut-brain (MGB) axis. Mice treated with fecal microbiota transplantation from PSP-treated mice exhibited improved depressive behaviors and increased levels of neurotransmitters 5-hydroxytryptamine and norepinephrine while reducing pro-inflammatory cytokines and corticosterone. Administration of PSP and fecal microbiota transplantation also regulated signaling pathways, indicating that PSP exerts its antidepressant effects through the MGB axis.

Zhang Y et al (2023).
Phytother Res.
PubMed:
36996849

assessment of antioxidant, neuroprotective, anti-urease and anti-tyrosinase capacities of leaves extracts.

Researchers analyzed the chemical contents of methanolic crude extract and its fractions (ethyl acetate, n-butanol, aqueous) using LC-MS analysis. They then tested the antioxidant properties (via DPPH, ABTS, etc. assays) and ability to inhibit enzymes (AChE, BChE, etc.). The study highlights the potential pharmacological properties of the extract and its potential for use in alternative medicine.

Anissa Trad Khodja E et al (2023).
J Tradit Chin Med.
PubMed:
36994513