GeoBotanical: All Studies

12721.

Broad-spectrum antiviral activity of Spatholobus suberectus Dunn against SARS-CoV-2, SARS-CoV-1, H5N1, and other enveloped viruses.

Scientists have found that an extract of Spatholobus suberectus Dunn (SSP), a medicinal plant, has broad-spectrum antiviral properties against SARS-CoV-1 and 2, HIV-1, and H5N1. SSP effectively inhibits viral entry, with EC values ranging from 3.6 to 5.1 μg/ml. Pre-treatment of pseudovirus or target cells with SSP showed consistent inhibitory activities with the respective EC value of 2.3 or 2.1 μg/ml. SSP blocked both SARS-CoV-2 spike glycoprotein and the host ACE2 receptor without toxic behavior. This plant extract has promising potential to be developed as a drug candidate for preventing and treating COVID-19 and other emerging enveloped viruses.

Antimicrobial COVID-19 Spatholobus suberectus

Liu Q et al (2022).; Phytother Res.
DOI:: 10.1002/ptr.7452
PubMed:: 35943221

12722.

Do Colletotrichum gloeosporioides and Rhizopus stolonifer induce alkaloidal and antifungal responses in Annona muricata seedlings?

Antimicrobial Phytochemistry Annona muricata

Riley-Saldaña CA et al (2022).; Z Naturforsch C J Biosci.
DOI:: 10.1515/znc-2021-0297
PubMed:: 35942979

12723.

Acidic polysaccharides from Buddleja officinalis inhibit angiogenesis via the Nrf2/ARE pathway to attenuate diabetic retinopathy.

Diabetes Buddleja officinalis

Zhu J et al (2022).; Food Funct.
DOI:: 10.1039/d2fo01075e
PubMed:: 35942925

12724.

Cardiogenic shock due to yew poisoning rescued by VA-ECMO: case report and literature review.

Cardiology Taxus baccata

Schreiber N et al (2022).; Channels (Austin).
DOI:: 10.1080/19336950.2022.2104886
PubMed:: 35942511

12725.

Characterization of the first Rubus yellow net virus genome from blackberry.

Genetics Rubus fruticosus

Vakić M et al (2022).; Virus Genes.
DOI:: 10.1007/s11262-022-01926-4
PubMed:: 35941271

12726.

Ameliorative effect of dandelion (Taraxacum officinale) peptides on benzo(a)pyrene-induced oxidative stress and inflammation in human umbilical vein endothelial cells.

Immunology Taraxacum officinale

Cai Z et al (2023).; J Pept Sci.
DOI:: 10.1002/psc.3447
PubMed:: 35940823

12727.

Effect of microwave heating on lipid composition, chemical properties and antioxidant activity of oils from Trichosanthes kirilowii seed.

Immunology Trichosanthes kirilowii

Xu L et al (2022).; Food Res Int.
DOI:: 10.1016/j.foodres.2022.111643
PubMed:: 35940816

12728.

Actinidin reduces gluten-derived immunogenic peptides reaching the small intestine in an in vitro semi-dynamic gastrointestinal tract digestion model.

Gastroenterology Actinidia deliciosa

Jayawardana IA et al (2022).; Food Res Int.
DOI:: 10.1016/j.foodres.2022.111560
PubMed:: 35940780