Therapeutic potential of the medicinal mushroom Ganoderma lucidum against Alzheimer's disease.

Ganoderma lucidum, a medicinal mushroom, shows potential as an adjuvant for Alzheimer's disease (AD) treatment. It can delay AD progression, improve cognitive function, and inhibit various mechanisms involved in AD pathology. More research and clinical trials are needed to fully understand its therapeutic potential.

Chen XJ et al (2024).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2024.116222

PubMed:

38310653

Chaenomeles sinensis (Thouin) Koehne fruit polyphenols alleviate high-fat diet-induced obesity and liver steatosis by improving lipid metabolism in mice.

CSFP from Chaenomeles sinensis fruit reduces body weight gain, triglycerides, and cholesterol in mice on a high-fat diet by modulating lipid metabolism pathways. This suggests potential health benefits for humans.

Song H et al (2024).

Nutr Res.

DOI:

10.1016/j.nutres.2024.01.008

PubMed:

38310647

Sophocarpine alleviates intestinal fibrosis via inhibition of inflammation and fibroblast into myofibroblast transition by targeting the Sirt1/p65 signaling axis.

Jiang R et al (2024).

Eur J Pharmacol.

DOI:

10.1016/j.ejphar.2024.176318

PubMed:

38309678

In-depth investigation of the therapeutic effect of Tribulus terrestris L. on type 2 diabetes based on intestinal microbiota and feces metabolomics.

Researchers investigated the effects of Tribulus terrestris L. (TT) fruit on diabetes. TT has been used in Tibetan medicine for centuries, but its mechanisms and effects on diabetes remained unknown.

Meng X et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2024.117815

PubMed:

38309487

Overexpression of a BR inactivating enzyme gene GhPAG1 impacts eggplant fruit development and anthocyanin accumulation mainly by altering hormone homeostasis.

Brassinosteroid deficiency in eggplants hinders fruit development and pigmentation, resulting in smaller, less colorful fruit. Genes responsible for cell elongation, hormone signaling, and pigment production were affected.

Yang Q et al (2024).

Plant Sci.

DOI:

10.1016/j.plantsci.2024.112014

PubMed:

38309473

Modulation of gut microbiota by crude mulberry polysaccharide attenuates knee osteoarthritis progression in rats.

Zheng YZ et al (2024).

Int J Biol Macromol.

DOI:

10.1016/j.ijbiomac.2024.129936

PubMed:

38309391

Distinct toxic effects, gene expression profiles, and phytohormone responses of Polygonatum cyrtonema exposed to two different antibiotics.

Yang G et al (2024).

J Hazard Mater.

DOI:

10.1016/j.jhazmat.2024.133639

PubMed:

38309169

Homoeologous exchanges contribute to branch angle variations in rapeseed: Insights from transcriptome, QTL-seq and gene functional analysis.

Sun C et al (2024).

Plant Biotechnol J.

DOI:

10.1111/pbi.14292

PubMed:

38308663