All Studies

New Monoterpenoid Indole Hybrids from Gelsemium elegans with Anti-Inflammatory and Osteoclast Inhibitory Activities.

Researchers discovered two new alkaloids, along with six known analogues, in Gelsemium elegans. These compounds showed anti-inflammatory activity and inhibited osteoclast formation, suggesting potential therapeutic applications for G. elegans.

Zhang PP et al (2023).
Chem Biodivers.
PubMed:
37968250

Steroidal Saponins from Solanum lyratum Thunb.

Researchers discovered four new steroidal compounds and isolated twenty known compounds from Solanum lyratum Thunb plants. Some of these compounds showed significant cytotoxic effects against human colon and hepatoma cells, offering potential for cancer treatment. This study also provides chemical markers to help differentiate Solanum plants.

Lai JX et al (2023).
Chem Biodivers.
PubMed:
37968243

OPHTHALMIC WILD OLIVE (ACEBUCHE) OIL NANOEMULSIONS EXERT OCULOPROTECTIVE EFFECTS AGAINST OXIDATIVE STRESS INDUCED BY ARTERIAL HYPERTENSION.

Scientists developed an olive oil-based formulation for ocular administration to counteract oxidative damage in hypertensive eye diseases. The formulation, tested in mice, reduced morphological alterations and demonstrated antioxidant effects, making it a promising therapy for ocular pathologies associated with hypertension.

Santana-Garrido A et al (2023).
Int J Pharm.
PubMed:
37967686

2023 International Consensus Guidance for the use of Tripterygium Wilfordii Hook F in the treatment of active rheumatoid arthritis.

Scientists investigated the effectiveness of Tripterygium wilfordii Hook F extract for treating rheumatoid arthritis. This herbal treatment has been used since the 1960s and could offer potential relief for RA symptoms.

Zhang X et al (2023).
J Autoimmun.
PubMed:
37967495

Chemical composition and antimicrobial activity of essential oils of two wild olive subspecies Olea europaea L.var. sylvestris and the endemic olive Olea europaea subsp. lapperinie from Algeria.

This research identified the chemical composition of two wild olive subspecies' oils. The oils showed efficient antibacterial activity, but one subspecies had a higher range of inhibition.

Bouchoucha S et al (2023).
Nat Prod Res.
PubMed:
37967031

Jerusalem artichoke diversity in Türkiye: comparative analysis of clone and organ-based biochemical composition.

Scientists analyzed 22 Jerusalem artichoke clones from Turkey, studying effects of clones and organs on biochemical parameters. They also investigated correlations between parameters and factors influencing dry matter in tubers, useful for lab decision-making.

Hanci F et al (2023).
Nat Prod Res.
PubMed:
37967018

One new prenylated flavonoid with cytotoxic activity from Epimedium brevicornu maxim.

Scientists discovered and identified four flavonoids from maxim leaves. One of them showed moderate cytotoxicity against Lewis Lung cancer cells, while the others had weak cytotoxic effects.

Zhang H et al (2023).
Nat Prod Res.
PubMed:
37966979