All Studies

Exploring the phenolic profile, antibacterial, and antioxidant properties of walnut leaves (Juglans regia L.).

This study analyzed phenolic compounds in walnut leaves from northern Iraq. The compounds showed antibacterial and antioxidant properties, making them potential candidates for antioxidant drugs to treat oxidative stress-related diseases.

Altemimi AB et al (2023).
Food Sci Nutr.
PubMed:
37970415

Flavonoids contribute most to discriminating aged Guang Chenpi (Citrus reticulata 'Chachi') by spectrum-effect relationship analysis between LC-Q-Orbitrap/MS fingerprint and ameliorating spleen deficiency activity.

Researchers found that after 5 years of storage, aged Guang Chenpi, a Chinese herbal medicine, had increased flavonoid content and improved anti-spleen deficiency effects in mice. The study revealed that aged Guang Chenpi also regulated gut microbiota through specific flavonoids, highlighting the potential benefits of long storage time for herbal medicines.

Sun X et al (2023).
Food Sci Nutr.
PubMed:
37970411

Assessing the multitargeted antidiabetic potential of three pomegranate peel-specific metabolites: An in silico and pharmacokinetics study.

In silico study found that three compounds in pomegranate peel (punicalin, punicalagin, and ellagic acid) interacted significantly with nine protein targets involved in diabetes management. These compounds show potential as antidiabetic agents, but further validation is needed.

Gull H et al (2023).
Food Sci Nutr.
PubMed:
37970376

Biosynthesis of Artemisia abyssinica Leaf Extract-Mediated Bimetallic ZnO-CuO Nanoparticles: Antioxidant, Anticancer, and Molecular Docking Studies.

A study synthesized plant extract-mediated metal oxide nanoparticles and evaluated their anticancer, antioxidant, and molecular binding efficacy. The biosynthesized nanoparticles showed potential as antioxidant and anticancer drug candidates, particularly for breast cancer. Cytotoxicity tests are recommended for further use.

Orshiso TA et al (2023).
ACS Omega.
PubMed:
37969984

Utilizing network pharmacology and experimental validation to explore the potential molecular mechanisms of raw Pinellia ternate in treating esophageal cancer.

Chinese medicine raw (RP) shows potential therapeutic benefits in treating esophageal cancer. This study used web-based pharmacological methods and cellular experiments to explore its effectiveness as a complementary approach to surgery and radiotherapy.

Liu Y et al (2023).
J Gastrointest Oncol.
PubMed:
37969842

Unraveling the serial glycosylation in the biosynthesis of steroidal saponins in the medicinal plant Paris polyphylla and their antifungal action.

Researchers discovered enzymes in a medicinal plant that produce bioactive compounds. They found that these enzymes are versatile and generated new compounds, including a potential antifungal agent.

Chen Y et al (2023).
Acta Pharm Sin B.
PubMed:
37969733

The effect of calorie-restriction along with thylakoid membranes of spinach on the gut-brain Axis Pathway and oxidative stress biomarkers in obese women with polycystic ovary syndrome: a Randomized, Double-blind, placebo-controlled clinical trial.

In this study, researchers investigated the effects of spinach supplementation and a hypocaloric diet on women with polycystic ovary syndrome (PCOS). They found that this intervention improved gut health, neurotrophic factor levels, and oxidative stress in PCOS patients.

Nikrad N et al (2023).
J Ovarian Res.
PubMed:
37968684

Integrated transcriptome and metabolome analysis unveils the mechanism of color-transition in Edgeworthia chrysantha tepals.

Researchers conducted theoretical research on Edgeworthia chrysantha, investigating its striking color transition during flowering. The study aims to uncover the regulatory mechanisms behind this process, providing valuable insights for cultivation and applications of this valuable plant.

Zhou N et al (2023).
BMC Plant Biol.
PubMed:
37968605