GeoBotanical: All Studies

5537.

Synergistic Antimicrobial Activity of Eugenol in Combination with Fosfomycin to Combat Escherichia coli and Potential Effect on Plasmid-Mediated Fosfomycin Resistance Genes.

This study found that a combination of Eugenol (from Syzygium aromaticum) and Fosfomycin could effectively inhibit multidrug-resistant Uropathogenic Escherichia coli. The genes fosA3 and fosA4, which contribute to Fosfomycin resistance, were present in a small percentage of isolates. These findings suggest a potential new treatment for bacterial infections.

Antimicrobial Genetics Syzygium aromaticum

Ibrahim AA and Mohammed RK (2023).; Chem Biodivers.
DOI:: 10.1002/cbdv.202301567
PubMed:: 37956152

5538.

Curcuminoids-enriched extract and its cyclodextrin inclusion complexes ameliorates arthritis in complete Freund's adjuvant-induced arthritic mice via modulation of inflammatory biomarkers and suppression of oxidative stress markers.

Arthritis Immunology Curcuma longa

Saleem U et al (2023).; Inflammopharmacology.
DOI:: 10.1007/s10787-023-01370-2
PubMed:: 37955785

5539.

HH-A, a modified honokiol, protects against cerebral ischemia/reperfusion induced brain injury in rodent via Nrf2/HO-1 signaling pathways.

Cardiology Neuroscience Magnolia officinalis

Zhang Y et al (2024).; Naunyn Schmiedebergs Arch Pharmacol.
DOI:: 10.1007/s00210-023-02816-8
PubMed:: 37955691

5540.

Piperlongumine: the amazing amide alkaloid from Piper in the treatment of breast cancer.

Piperlongumine inhibits breast cancer cells, induces apoptosis, and impacts signaling pathways. Its potential in cancer treatment is enhanced by nanotechnology. Future research is needed to understand its chemistry, bioavailability, and toxicity.

Cancer Phytochemistry Piper longum

Mitra S et al (2023).; Naunyn Schmiedebergs Arch Pharmacol.
DOI:: 10.1007/s00210-023-02673-5
PubMed:: 37955690

5541.

Genome-wide association studies using multi-models and multi-SNP datasets provide new insights into pasmo resistance in flax.

Genetics Linum usitatissimum

He L et al (2023).; Front Plant Sci.
DOI:: 10.3389/fpls.2023.1229457
PubMed:: 37954993

5542.

Phyllanthus emblica: a comprehensive review of its phytochemical composition and pharmacological properties.

The review explores the various health benefits of the Balakka fruit, which include antioxidant, anti-aging, anti-cholesterol, anti-diabetic properties, among others. It also examines the different bioactive compounds present in the fruit.

Phytochemistry Phyllanthus emblica

Prananda AT et al (2023).; Front Pharmacol.
DOI:: 10.3389/fphar.2023.1288618
PubMed:: 37954853

5543.

Analysis of the heavy metal contents' effect on steroidal saponins and the anti-breast cancer activity of Paris polyphylla var. yunnanensis.

The study analyzed the heavy metal content and saponins in a Chinese medicinal plant (var.) used for centuries. They found that high heavy metal content reduced the anti-breast cancer activity. Controlling heavy metal content is important in cultivating var. for medicinal purposes.

Cancer Phytochemistry Paris polyphylla

Li HL et al (2023).; Front Pharmacol.
DOI:: 10.3389/fphar.2023.1277395
PubMed:: 37954839

5544.

The Antidiabetic Activity of Combining the Aqueous Extracts of Vernonia amygdalina Leaves and Tamarindus indica Fruit Pulp in Streptozotocin-Induced Wistar Rats.

Researchers investigated the antioxidant and antidiabetic activities of a combination of and extracts. The combination showed significant reduction in diabetes-related markers and could be beneficial for diabetic patients.

Diabetes Tamarindus indica Vernonia amygdalina

Tekou FA et al (2023).; Cureus.
DOI:: 10.7759/cureus.46807
PubMed:: 37954696