The Effects of Crocus sativus (Saffron) on ADHD: A Systematic Review.

Study evaluated saffron extracts for ADHD treatment, assessing effectiveness and safety. Important for lab decisions due to saffron's popularity and potential as a traditional plant remedy.

Seyedi-Sahebari S et al (2023).

J Atten Disord.

DOI:

10.1177/10870547231203176

PubMed:

37864351

Transcriptome and metabolome analyses revealed the response mechanism of pepper roots to Phytophthora capsici infection.

Researchers investigated the defense response of pepper roots to Phytophthora capsici infection, a destructive disease in pepper production. Understanding this molecular mechanism can help develop effective strategies for disease management.

Lei G et al (2023).

BMC Genomics.

DOI:

10.1186/s12864-023-09713-7

PubMed:

37864214

Insights into the missing apiosylation step in flavonoid apiosides biosynthesis of Leguminosae plants.

Researchers discovered an enzyme that efficiently catalyzes the apiosylation of flavonoid glycosides, identified key sugar-binding motifs, obtained mutants with altered sugar selectivity, and synthesized flavonoid apiosides. This has implications for understanding apioside biosynthesis and phenolic apiosyltransferase applications.

Wang HT et al (2023).

Nat Commun.

DOI:

10.1038/s41467-023-42393-1

PubMed:

37863881

Antidepressant effects of 70% ethanolic extract of Lonicerae japonicae flos and it contained chlorogenic acid via upregulation of BDNF-TrkB pathway in the hippocampus of mice.

Lonicera japonica flos (LJF) extract and chlorogenic acid (CGA) show significant antidepressant effects, correlating with CGA content. LJF-70% ethanolic extract and CGA improve depressive behavior, upregulate BDNF-TrkB pathway, restore hippocampal neurons, and protect the liver.

Qin L et al (2023).

Brain Res Bull.

DOI:

10.1016/j.brainresbull.2023.110796

PubMed:

37863440

Feeding alfalfa-grass or red clover-grass mixture baleage: Effect on milk yield and composition, ruminal fermentation and microbiota taxa relative abundance, and nutrient utilization in dairy cows.

Lange MJ et al (2024).

J Dairy Sci.

DOI:

10.3168/jds.2023-23836

PubMed:

37863298

Protective effects and mechanisms of Momordica charantia polysaccharide on early-stage diabetic retinopathy in type 1 diabetes.

This study found that Momordica charantia polysaccharide (MCP) can potentially prevent and alleviate diabetes mellitus (DM) and diabetic retinopathy (DR) by improving body weight, inflammation, and apoptosis in retinal tissues. MCP may be a promising medication for DM and a natural medicine for DR.

Liu J et al (2023).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2023.115726

PubMed:

37862973

A high throughput method for detection of cyclooxygenase-2 enzyme inhibitors by effect-directed analysis applying high performance thin layer chromatography-bioassay-mass spectrometry.

Scientists developed a method to detect bioactive molecules that inhibit the COX-2 enzyme using a combination of bioassay, chromatography, and mass spectrometry. They optimized the conditions and used it to identify COX-2 inhibitors in Chiloe's giant garlic extract.

Oyarzún P et al (2023).

J Chromatogr A.

DOI:

10.1016/j.chroma.2023.464426

PubMed:

37862751

Green Pea (Pisum sativum L.) Hull Polyphenol Extract Alleviates NAFLD through VB6/TLR4/NF-κB and PPAR Pathways.

Green pea hull extract can relieve nonalcoholic fatty liver disease in mice by reducing fat accumulation and improving antioxidant activity and lipid and glucose metabolism. Vitamin B6 plays a key role in this process, potentially leading to new treatments for NAFLD.

Guo F et al (2023).

J Agric Food Chem.

DOI:

10.1021/acs.jafc.3c02337

PubMed:

37861789