Identification of novel inhibitors from Urtica spp against TNBC targeting JAK2 receptor for breast cancer therapy.

Researchers discovered extracts from Urtica dioica and U. parviflora plants containing 12 compounds with better binding energy than Paclitaxel. These extracts showed promising anticancer activity against TNBC cells while being less toxic to healthy cells, hinting at herbal-based drug development for breast cancer.

Upreti S et al (2023).

Med Oncol.

DOI:

10.1007/s12032-023-02193-5

PubMed:

37806999

Assessment of the anti-inflammatory mechanism of quercetin 3,7-dirhamnoside using an integrated pharmacology strategy.

He X et al (2023).

Chem Biol Drug Des.

DOI:

10.1111/cbdd.14346

PubMed:

37806949

Occurrence and fate of antibiotic-resistance genes and their potential hosts in high-moisture alfalfa silage treated with or without formic acid bactericide.

Silage can contain antibiotic resistance genes (ARGs) that pose a latent health risk to animals. Formic acid treatment reduced ARGs initially but increased their abundance after 90 days. Pathogens like Staphylococcus and Clostridium may act as ARG hosts. Microbes are the main driver of ARG propagation in silage.

Zhang X et al (2023).

J Environ Manage.

DOI:

10.1016/j.jenvman.2023.119235

PubMed:

37806267

Genome-wide identification and comprehensive analysis of WRKY transcription factor family in safflower during drought stress.

Song X et al (2023).

Sci Rep.

DOI:

10.1038/s41598-023-44340-y

PubMed:

37805641

Evaluation of anticancer effect of colchicum autumnale L. Corm on breast cancer cell.

Study evaluated anticancer effect of colchicum autumnale L. Corm on breast cancer cells. Medicinal plants could potentially prevent and inhibit breast cancer. Important for lab decisions on cancer research.

Falahianshafiei S et al (2023).

BMC Complement Med Ther.

DOI:

10.1186/s12906-023-04189-0

PubMed:

37805533

Antimicrobial and anti-aflatoxigenic activities of nanoemulsions based on Achillea millefolium and Crocus sativus flower extracts as green promising agents for food preservatives.

Nanoemulsions made from natural extracts can potentially be used as antimicrobial and anti-aflatoxigenic agents, making them effective for food preservation and safety. However, more research is needed to understand their mechanism of action.

Abu Safe FA et al (2023).

BMC Microbiol.

DOI:

10.1186/s12866-023-03033-2

PubMed:

37805450

Study of the anti-inflammatory properties of a thick extract of Tribulus terrestris L.

Yunusova S et al (2023).

Ceska Slov Farm.

PubMed:

37805264

Kurarinone exerts anti-inflammatory effect via reducing ROS production, suppressing NLRP3 inflammasome, and protecting against LPS-induced sepsis.

Yazal T et al (2023).

Biomed Pharmacother.

DOI:

10.1016/j.biopha.2023.115619

PubMed:

37804813