All Studies

Cell-based screen identifies porphyrins as FGFR3 activity inhibitors with therapeutic potential for achondroplasia and cancer.

Researchers developed an assay system to monitor FGFR3 activation and discovered that two porphyrins and an extract from Amaranthus viridis can reduce overactive FGFR3 signaling in multiple myeloma cells and chondrocytes, as well as improve bone growth in mice. These findings offer a new strategy for identifying potential treatments for FGFR3-related diseases.

Lin YW et al (2023).
JCI Insight.
PubMed:
37824212

Characterization of caffeoyl shikimate esterase gene family identifies CsCSE5 as a positive regulator of Podosphaera xanthii and Corynespora cassiicola pathogen resistance in cucumber.

Yu Y et al (2023).
Plant Cell Rep.
PubMed:
37823975

Oxidative stress in liver of streptozotocin-induced diabetic mice fed a high-fat diet: A treatment role of Artemisia annua L.

Artemisia annua extracts improved liver function and reduced oxidative stress in diabetic mice, showing comparable or greater antioxidant activity than metformin.

Ghanbari M et al (2023).
Endocr Regul.
PubMed:
37823572

Jackfruit waste: an invented anticancer therapy using Jacalin lectin from jackfruit seed.

Study explores use of jackfruit seeds as functional ingredients for novel treatments for diseases like cancer, highlighting their therapeutic properties. Potential for consuming seeds as dietary food to prevent and treat cancer and other lifestyle diseases is also discussed.

Ghosh P et al (2023).
Anticancer Drugs.
PubMed:
37823283

Anticancer assessment and antibiofilm potential of Laetiporus sulphureus mushroom originated from Serbia.

The Bull. Murrill mushroom extract has antimicrobial, antioxidant, and anticancer properties. It protects probiotics and inhibits cancer cell motility without being cytotoxic.

Jovanović MM et al (2023).
Food Sci Nutr.
PubMed:
37823160