Integrated bioinformatics analysis for the identification of idiopathic pulmonary fibrosis-related genes and potential therapeutic drugs.

Zhang Z et al (2023).

BMC Pulm Med.

DOI:

10.1186/s12890-023-02678-z

PubMed:

37794454

Multi-omics analysis reveals the molecular basis of flavonoid accumulation in fructus of Gardenia (Gardenia jasminoides Ellis).

Researchers analyzed the genetic and metabolic makeup of gardenia fruits at different stages of growth, uncovering a network that controls the production of beneficial compounds with antioxidant, anti-inflammatory, and anticancer properties. This study identifies important genes involved in flavonoid synthesis.

Chen J et al (2023).

BMC Genomics.

DOI:

10.1186/s12864-023-09666-x

PubMed:

37794356

DNA fragmentation, chromosomal aberrations, and multi-toxic effects induced by nickel and the modulation of Ni-induced damage by pomegranate seed extract in Allium cepa L.

This study found that pomegranate seed extract (PSEx) can help protect against nickel (Ni)-induced damage in plants. PSEx reduced DNA damage, improved physiological parameters, and restored cell structures affected by Ni exposure. This suggests that PSEx could be beneficial in mitigating the negative effects of Ni and promoting recovery.

Yılmaz H et al (2023).

Environ Sci Pollut Res Int.

DOI:

10.1007/s11356-023-30193-5

PubMed:

37794225

Antioxidative and neuroprotective potential of Acorus calamus linn. and Cordia dichotoma G. Forst. In Alzheimer's type dementia in rodent.

The researchers tested plant extracts of Acorus calamus and Cordia dichotoma on mice with Alzheimer's-like symptoms caused by scopolamine. The extracts improved behavioral and biochemical parameters, indicating potential for treating cognitive disorders and neurodegenerative diseases.

Malik R et al (2023).

Brain Res.

DOI:

10.1016/j.brainres.2023.148616

PubMed:

37793605

Wild and cultivated olive trees: Nutraceutical insights of extra virgin olive oils in cardiovascular and ocular diseases.

Extra virgin olive oil (EVOO) and ACE oil from wild olive variety contain bioactive molecules that have anti-inflammatory, antioxidant, anti-cancer properties. They can help prevent cardiovascular diseases, ocular diseases, and have potential as prebiotic compounds.

Reyes-Goya C et al (2023).

Biochim Biophys Acta Mol Basis Dis.

DOI:

10.1016/j.bbadis.2023.166904

PubMed:

37793462

A Comprehensive Review on Botany, Phytochemistry, Traditional Uses, Pharmacology, Analytical Methods, Processing Methods, Pharmacokinetics and Toxicity of Pulsatilla chinensis.

Researchers conducted a study on Pulsatilla chinensi and its potential clinical uses. They aim to support future research and advancement in this field. Importance lies in understanding the potential benefits and applications of Pulsatilla chinensi for possible use in clinical settings.

Leng D et al (2023).

Altern Ther Health Med.

PubMed:

37793336

Punica granatum peel extract modulates levofloxacin-induced oxidative stress and testicular damage in rats.

Pomegranate peel extract may protect against levofloxacin-induced testicular damage, reversing oxidative stress, hormonal changes, and apoptosis in rats.

El-Demerdash FM, Ahmed MM and Baghdadi HH (2023).

Tissue Cell.

DOI:

10.1016/j.tice.2023.102227

PubMed:

37793207

Extract of Cimicifuga racemosa (L.) Nutt protects ovarian follicle reserve of mice against in vitro deleterious effects of dexamethasone.

CIMI extract counteracts the harmful effects of DEXA on mouse ovaries in vitro, maintaining follicle morphology, stromal cellular density, and gene expression levels of Bax, Bcl-2, and Caspase-3 similar to control. CIMI can protect ovaries from DEXA-induced damage.

Assis EIT et al (2023).

Braz J Med Biol Res.

DOI:

10.1590/1414-431X2023e12811

PubMed:

37792779