All Studies

Withaferin A: A Dietary Supplement with Promising Potential as an Anti-Tumor Therapeutic for Cancer Treatment - Pharmacology and Mechanisms.

Tldr: Withaferin A (WA), a compound from a dietary supplement, shows significant anti-tumor effects by inhibiting cell cycle, apoptosis, metastasis, and angiogenesis. It has potential targets for cancer treatment, but toxicity and bioavailability issues need addressing. Further research on its exact mechanism is crucial.

Xing Z et al (2023).
Drug Des Devel Ther.
PubMed:
37753228

Neutral polysaccharide from Gastrodia elata alleviates cerebral ischemia-reperfusion injury by inhibiting ferroptosis-mediated neuroinflammation via the NRF2/HO-1 signaling pathway.

This study looked at how a polysaccharide from Gastrodia elata called NPGE affects the interaction between ferroptosis and neuroinflammation during cerebral ischemia-reperfusion injury. It found that NPGE has potential effects against oxidative stress and inflammation in CIRI neuropathology.

Zhang Y et al (2023).
CNS Neurosci Ther.
PubMed:
37752806

Two new quinolinone glycoalkaloids from Chrysanthemum indicum L. and their antimicrobial activity.

Researchers discovered two new compounds in L. plant through phytochemical investigation. Compound demonstrated significant antimicrobial effects against various pathogens, making it potentially valuable for developing new antimicrobial drugs.

Zhu Q et al (2023).
Nat Prod Res.
PubMed:
37752790

Unleashing the Potential of Benincasa hispida Peel Extract: Synthesizing Selenium Nanoparticles with Remarkable Antibacterial and Anticancer Properties.

Researchers used ash gourd extract to synthesize selenium nanoparticles with unique properties. These nanoparticles have antibacterial effectiveness, spherical shape, and potential for fighting cancer. They are also non-toxic to human osteoblasts, making them promising for medical applications.

Khan S et al (2023).
Mol Biotechnol.
PubMed:
37752300