All Studies

In silico guided screening of active components of C. lanceolata as 3-chymotrypsin-like protease inhibitors of novel coronavirus.

Researchers conducted computational screening of phytoconstituents from a specific plant to identify potential antiviral hit candidates against 3CLpro, a target for COVID-19 treatment. Stigmasterol showed the highest binding affinity and exhibited stable interactions. This study suggests as a potential drug candidate for further development against the virus.

COVID-19 Codonopsis lanceolata
Sharma G et al (2023).
3 Biotech.
DOI:
10.1007/s13205-023-03745-2
PubMed:
37663751

Nephroprotective effects of Datura stramonium leaves against methotrexate nephrotoxicity via attenuation of oxidative stress-mediated inflammation and apoptosis in rats.

Researchers investigated whether a leaf extract could counteract the kidney-damaging side effects of the anticancer drug methotrexate in rats. This study is relevant for improving the clinical application of methotrexate in cancer treatments.

Immunology Datura stramonium
Alum EU et al (2023).
Avicenna J Phytomed.
DOI:
10.22038/AJP.2023.21903
PubMed:
37663387

Herbal medicines in the treatment of children and adolescents with attention-deficit/hyperactivity disorder (ADHD): An updated systematic review of clinical trials.

This study reviewed herbal medicines and phytochemicals for treating ADHD in children. It offers an updated analysis to aid in making informed decisions for pediatric ADHD treatment.

Neuroscience Hypericum perforatumMelissa officinalisPassiflora incarnataValeriana officinalis
Golsorkhi H et al (2023).
Avicenna J Phytomed.
DOI:
10.22038/AJP.2022.21115
PubMed:
37663386

Lavender (Lavandula angustifolia) syrup as an adjunct to standard care in patients with mild to moderate COVID-19: An open-label, randomized, controlled clinical trial.

This study investigated the effectiveness of lavender syrup, alongside standard care, for patients with mild to moderate COVID-19 symptoms. Understanding its potential benefits can help scientists make informed decisions regarding treatment options for COVID-19 patients.

COVID-19 Lavandula angustifolia
Qaraaty M et al (2023).
Avicenna J Phytomed.
DOI:
10.22038/AJP.2022.21606
PubMed:
37663382

The antidepressant effect of combined extracts of Hypericum perforatum and Echium amoenum supplementation in patients with depression symptoms: A randomized clinical trial.

The study evaluated the effectiveness of and extracts in treating mild to moderate depression. Traditional Iranian medicine uses dried flowers for mental disorder therapy.

Neuroscience Hypericum perforatum
Sadeghi A et al (2023).
Avicenna J Phytomed.
DOI:
10.22038/AJP.2023.21707
PubMed:
37663381

Genome-wide identification of Apetala2 gene family in Hypericum perforatum L and expression profiles in response to different abiotic and hormonal treatments.

Tossers identified HpAP2 genes to study their functions in plant development, hormonal response, and stress. Findings can aid in understanding how these genes affect plant growth and survival.

EndocrinologyGenetics Hypericum perforatum
Li Y et al (2023).
PeerJ.
DOI:
10.7717/peerj.15883
PubMed:
37663289

Invitro and in vivo anthelmintic efficacy of peppermint (Mentha x piperita L.) essential oil against gastrointestinal nematodes of sheep.

Peppermint essential oil showed potential as an alternative treatment for sheep with gastrointestinal nematode infections. It had ovicidal activity and some effectiveness as an anthelmintic, with no observed toxicity. More research is needed to evaluate its safety and effectiveness in real-world conditions and against resistant nematodes.

Phytochemistry Mentha x piperita
Štrbac F et al (2023).
Front Vet Sci.
DOI:
10.3389/fvets.2023.1232570
PubMed:
37662995

Antifungal action and targeted mechanism of Bio fabricated zinc oxide (ZnO) nanoparticles against Ascochytafabae.

This study examined the structure and properties of ZnO nanoparticles, synthesized using the sol gel method. The nanoparticles showed strong anti-fungal efficacy against Ascochytafabae, a fungus causing blight disease in beans. Important findings include a median diameter in the nanometer range and a band gap energy of 3.22eV.

Antimicrobial Phaseolus vulgaris
Sharma I et al (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e19179
PubMed:
37662815
1 839 848 849 850 859 2617