RNA Sequencing and Bioinformatics Analysis Reveals the Downregulation of DNA Replication Genes by Morindone in Colorectal Cancer Cells.

Morindone, a natural compound, shows promise as a treatment for colorectal cancer (CRC). It downregulates genes involved in DNA replication and cell development. GINS2 is identified as a potential target. Validation confirms these findings. Consider using morindone for CRC treatment.

Chee CW et al (2023).

Appl Biochem Biotechnol.

DOI:

10.1007/s12010-023-04690-9

PubMed:

37642925

Antitumor and antibacterial activity of metabolites of endophytic Colletotrichum siamense isolated from coffee (Coffea arabica L. cv IAPAR-59).

Researchers analyzed the chemical profile of endophytic fungus Colletotrichum siamense from coffee plants and found potential compounds with pharmacological and antibacterial activity. This could be beneficial for the pharmaceutical and biotechnological industries.

do Espírito Santo BC et al (2023).

Braz J Microbiol.

DOI:

10.1007/s42770-023-01104-0

PubMed:

37642890

Neuroprotective effect of Potentilla reptans L. root in the rat brain global ischemia/reperfusion model.

Potentilla reptans root extract shows potential for protecting the brain and reducing beta-amyloid in a rat model, indicating possible benefits for stroke and neurodegenerative diseases.

Noorgaldi S et al (2023).

Arch Pharm (Weinheim).

DOI:

10.1002/ardp.202300363

PubMed:

37642540

Genus Gelsemium and its endophytic fungi - Comprehensive review of their traditional uses, phytochemistry, pharmacology, and toxicology.

Gelsemium plants are popular for their medicinal properties, treating various issues like skin problems, neuralgia, fractures, and cancer. They are also used to reduce inflammation and blood flow to spinal and cerebrospinal centers.

Peng YL et al (2023).

Curr Top Med Chem.

DOI:

10.2174/1568026623666230825105233

PubMed:

37642181

Leaf relative water content at 50% stomatal conductance measured by noninvasive NMR is linked to climate of origin in nine species of eucalypt.

Coleman D et al (2023).

Plant Cell Environ.

DOI:

10.1111/pce.14700

PubMed:

37641435

Solanum americanum genome-assisted discovery of immune receptors that detect potato late blight pathogen effectors.

Scientists studied Solanum americanum, a blight-resistant relative of potato and tomato, to identify three genes that recognize P. infestans (the cause of late blight) effectors. This research can help engineer blight-resistant crops.

Lin X et al (2023).

Nat Genet.

DOI:

10.1038/s41588-023-01486-9

PubMed:

37640880

Performance and antioxidant traits of broiler chickens fed with diets containing rapeseed or flaxseed oil and optimized quercetin.

Quercetin was added to diets with rapeseed or flaxseed oil for broiler chickens. The optimized quercetin improved weight gain and overall body weight. Adding quercetin can reduce negative effects of oxidized lipids and is economically beneficial for animal nutrition.

Sierżant K et al (2023).

Sci Rep.

DOI:

10.1038/s41598-023-41282-3

PubMed:

37640806

Green synthesis of copper oxide nanoparticles and its efficiency in degradation of rifampicin antibiotic.

The study used Parthenium hysterophorus plant extract to create copper oxide nanoparticles (CuO NPs). The NPs were characterized using various techniques and found to have potential in remediation of environmental pollution caused by antibiotics.

Nzilu DM et al (2023).

Sci Rep.

DOI:

10.1038/s41598-023-41119-z

PubMed:

37640783