A New Saponin (Zygo-albuside D) from Zygophyllum album Roots Triggers Apoptosis in Non-Small Cell Lung Carcinoma (A549 Cells) through CDK-2 Inhibition.

Researchers isolated a new compound (Zygo-albuside D) from the root extract of an unknown plant, along with two known compounds. Zygo-albuside D showed promising cytotoxicity against cancer cells and induced apoptotic cell death. It also inhibited a specific target (CDK-2) and showed potential as an anticancer agent.

Eltamany EE et al (2023).

ACS Omega.

DOI:

10.1021/acsomega.3c04314

PubMed:

37636931

The relative role of soil, climate, and genotype in the variation of nutritional value of Annona senegalensis fruits and leaves.

Donhouedé JCF et al (2023).

Heliyon.

DOI:

10.1016/j.heliyon.2023.e19012

PubMed:

37636399

Analysis of the main bioactive compounds from Ocimum basilicum for their antimicrobial and antioxidant activity.

Scientists found that basil leaf extract prepared using ethanol and methanol showed strong antimicrobial activity against VRE infections, along with antioxidant properties. Gas chromatography-mass spectrometry analysis identified 19 compounds with therapeutic and food applications.

Backiam ADS et al (2023).

Biotechnol Appl Biochem.

DOI:

10.1002/bab.2508

PubMed:

37635658

Cross-species oncogenomics offers insight into human muscle-invasive bladder cancer.

Scientists studied urothelial carcinoma (UC) in dogs, cats, and cattle exposed to a carcinogen. UC in these animals share similarities with aggressive bladder cancer in humans. Understanding these models can help develop strategies to identify key factors driving the disease in humans.

Wong K et al (2023).

Genome Biol.

DOI:

10.1186/s13059-023-03026-4

PubMed:

37635261

Fatty acid composition and genome-wide associations of a chickpea (Cicer arietinum L.) diversity panel for biofortification efforts.

Researchers measured fatty acid levels in a chickpea panel, finding diverse concentrations. Genetic markers associated with one fatty acid were identified, suggesting potential for breeding chickpeas for improved health benefits and stress responses.

Salaria S et al (2023).

Sci Rep.

DOI:

10.1038/s41598-023-41274-3

PubMed:

37635199

Comparing the effect of aromatherapy with breast milk, Lavandula stoechas, and Rosa damascena on venipuncture pain in preterm infants.

This study compared the effects of aromatherapy with breast milk, Lavandula stoechas, and Rosa damascena on reducing venipuncture pain in preterm infants, who frequently undergo painful procedures. Finding effective non-pharmacological pain management methods is important for their well-being.

Askarinia S et al (2023).

Explore (NY).

DOI:

10.1016/j.explore.2023.08.002

PubMed:

37635050

Systemic treatments in Parthenium dermatitis: A systematic review and meta-analysis.

This study reviewed published research on systemic treatments for Parthenium dermatitis and found that azathioprine is the most effective treatment based on clinical severity scores. 88.8% of patients had a good response to azathioprine.

Akham R et al (2023).

Contact Dermatitis.

DOI:

10.1111/cod.14406

PubMed:

37634936

Genome-wide analysis of the SMXL gene family in common bean and identification of karrikin-responsive PvSMXL2 as a negative regulator of PEG-induced drought stress.

Fang P et al (2023).

Gene.

DOI:

10.1016/j.gene.2023.147741

PubMed:

37634881