All Studies

Multi-environment association study highlights candidate genes for robust agronomic quantitative trait loci in a novel worldwide Capsicum core collection.

Researchers used genome-wide association studies (GWAS) on a diverse subset of Capsicum annuum accessions to identify genetic determinants of agronomic traits. They identified candidate genes and found this research can aid in marker-assisted selection and breeding efforts.

Genetics Capsicum annuum
McLeod L et al (2023).
Plant J.
DOI:
10.1111/tpj.16425
PubMed:
37602679

Ophiopogonin D ameliorates non‑alcoholic fatty liver disease in high‑fat diet‑induced obese mice by improving lipid metabolism, oxidative stress and inflammatory response.

This study examined the effects of Ophiopogonin D (OP-D) on non-alcoholic fatty liver disease (NAFLD) in mice. OP-D was found to improve NAFLD by regulating lipid metabolism, antioxidant, and anti-inflammatory responses. OP-D also reduced lipogenesis and inflammation, potentially through the NF-κB signaling pathway.

ImmunologyObesity Ophiopogon japonicus
Huang X et al (2023).
Exp Ther Med.
DOI:
10.3892/etm.2023.12116
PubMed:
37602303

Inhibitory effects of Jasminum grandiflorum L. essential oil on lipopolysaccharide-induced microglia activation-integrated characteristic analysis of volatile compounds, network pharmacology, and BV-2 cell.

This study analyzes the volatile compounds in L. flowers and evaluates the inhibitory effects of L. essential oil on microglia activation. The findings suggest that L. essential oil can inhibit overactivation of microglia, reducing neuroinflammation and oxidative stress responses in Alzheimer's disease.

Phytochemistry Jasminum grandiflorum
Lu J et al (2023).
Front Pharmacol.
DOI:
10.3389/fphar.2023.1180618
PubMed:
37601063

Oxymatrine relieves high-fructose/fat-induced obesity via reprogramming the activity of lipid metabolism-related enhancer.

Researchers studied the effects of a high-fructose and high-fat diet on obesity and fatty liver disease. Their findings can help develop new treatments for these common metabolic disorders.

Obesity Sophora flavescens
Ren L et al (2023).
Front Endocrinol (Lausanne).
DOI:
10.3389/fendo.2023.1145575
PubMed:
37600712

Quality Control of 11 Cannabinoids by Ultraperformance Liquid Chromatography Coupled with Mass Spectrometry (UPLC-MS/MS).

Researchers analyzed the accuracy of cannabinoid labels in commercial hemp products. This is important because incorrect labeling affects consumers' ability to make informed decisions about their usage.

Phytochemistry Cannabis sativa
Duzan A, Reinken D and Basti MM (2023).
J Anal Methods Chem.
DOI:
10.1155/2023/3753083
PubMed:
37600560

Integrating network pharmacology and experimental studies for uncovering the molecular mechanisms of Dioscorea bulbifera L. in the treatment of thyroid cancer.

HYZ, a traditional Chinese medicine, shows promise in treating thyroid cancer by improving symptoms and reducing tumor volume. However, the exact mechanism of HYZ's action is still unknown.

CancerEndocrinology Dioscorea bulbifera
Liu Z et al (2023).
Heliyon.
DOI:
10.1016/j.heliyon.2023.e18886
PubMed:
37600377

A chromosome-scale and haplotype-resolved genome assembly of carnation (Dianthus caryophyllus) based on high-fidelity sequencing.

Scientists assembled the genome of carnation, a popular cut flower, at the chromosome level. They identified structural variations and transposable elements, and estimated the species differentiation time. The genome facilitates molecular biology and evolutionary studies.

Genetics Dianthus caryophyllus
Jiang H et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1230836
PubMed:
37600187

Assembly and analysis of the mitochondrial genome of Prunella vulgaris.

The study reports the first complete mitochondrial genome of (Lamiaceae), revealing gene content, codon preference, intercellular gene transfer, phylogeny, and RNA editing. The findings contribute to understanding the biology of and can inform future research studies.

Genetics Prunella vulgaris
Sun Z et al (2023).
Front Plant Sci.
DOI:
10.3389/fpls.2023.1237822
PubMed:
37600185
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