In silico studies on the phytochemical components of Lagenaria siceraria targeting aromatase receptors against breast cancer.

This study investigated the potential use of natural compounds against breast cancer. Five substances showed higher binding affinity than a commonly used treatment, Tamoxifen.

Samajdar S and Mondal P (2023).

In Silico Pharmacol.

DOI:

10.1007/s40203-023-00155-3

PubMed:

37525849

Potentilla reptans L. preconditioning regulates H19 and MIAT long noncoding RNAs in H9C2 myoblasts Ischemia/Reperfusion model.

PEF from P. reptans root improved cell viability and reduced apoptosis in H9C2 myoblasts under I/R conditions by regulating lncRNAs H19 and MIAT. Cardioprotective potential.

Mirzaei H et al (2023).

BMC Complement Med Ther.

DOI:

10.1186/s12906-023-04071-z

PubMed:

37525174

Screening of Phyllanthus niruri Leaves Phytoconstituents for Antiviral and Antibacterial Activity by Molecular Docking Studies.

Phyllanthus plants contain various compounds with potential antioxidant, anti-inflammatory, analgesic, antiulcer, antiviral, antitumor, and other health benefits. Docking experiments were performed to assess their potential activities against specific proteins. The results were compared to benchmark drugs ritonavir and ampicillin.

Manisha P et al (2023).

Adv Exp Med Biol.

DOI:

10.1007/978-3-031-31978-5_9

PubMed:

37525036

MAT as a promising therapeutic strategy against triple-negative breast cancer via inhibiting PI3K/AKT pathway.

Matrine (MAT), extracted from Sophora flavescens, inhibits TNBC cell proliferation and invasion, induces apoptosis and autophagy, and inhibits the PI3K/AKT signaling pathway. Promising for TNBC treatment.

Wei S et al (2023).

Sci Rep.

DOI:

10.1038/s41598-023-39655-9

PubMed:

37524857

Chromosome-level genome assembly and population genomics of Robinia pseudoacacia reveal the genetic basis for its wide cultivation.

Wang Z et al (2023).

Commun Biol.

DOI:

10.1038/s42003-023-05158-6

PubMed:

37524773

The comparative perspective of phytochemistry and biological properties of the Apiaceae family plants.

Hamidian M et al (2023).

Sci Rep.

DOI:

10.1038/s41598-023-39254-8

PubMed:

37524766

Anti-inflammatory Effects of Ziziphus Jujube Mill on LPS-induced Acute Lung Injury in Mice.

Z.J extract reduced inflammation in mice with acute lung injury (ALI) caused by LPS. It decreased inflammatory cells, wet-to-dry ratio, lung damage, and TNF-α levels. Z.J could be a potential therapy for ALI.

Shaban P et al (2023).

Iran J Allergy Asthma Immunol.

DOI:

10.18502/ijaai.v22i3.13056

PubMed:

37524664

Synthesis, antioxidant, antiproliferative activity, molecular docking and DFT studies of novel isoxazole derivatives of diosgenin, a steroidal sapogenin from Dioscorea deltoidea.

Diosgenin derivatives were synthesized and tested for antioxidant and anticancer activity against breast cancer cell lines. Two compounds showed high efficacy, suggesting potential drug candidates.

Yatoo GN and Banday JA (2023).

Fitoterapia.

DOI:

10.1016/j.fitote.2023.105621

PubMed:

37524127