Extraction, Characterization, and Evaluation of the Cytotoxic Activity of Piperine in Its Isolated form and in Combination with Chemotherapeutics against Gastric Cancer.

Scientists have developed reliable, low-cost methods to extract piperine from black pepper. Piperine has shown good cytotoxic activity against aggressive gastric cancer cells, and can enhance the effectiveness of traditional chemotherapeutic drugs. It is a promising molecule for therapy investigations.

Ramos INF et al (2023).

Molecules.

DOI:

10.3390/molecules28145587

PubMed:

37513459

The Antiproliferative Activity of Adiantum pedatum Extract and/or Piceatannol in Phenylhydrazine-Induced Colon Cancer in Male Albino Rats: The miR-145 Expression of the PI-3K/Akt/p53 and Oct4/Sox2/Nanog Pathways.

Adiantum pedatum extract and piceatannol protected against colon cancer by reducing oxidative damage, apoptosis, and histopathological changes in male albino rats. They may act through antioxidant and apoptotic pathways.

Khamis T et al (2023).

Molecules.

DOI:

10.3390/molecules28145543

PubMed:

37513415

Antimicrobial and Apoptotic Efficacy of Plant-Mediated Silver Nanoparticles.

Researchers synthesized silver nanoparticles (Ag-NPs) using tansy extracts and found they have higher cytotoxic activity against certain cancer cells and bactericidal properties.

Radzikowska-Büchner E et al (2023).

Molecules.

DOI:

10.3390/molecules28145519

PubMed:

37513392

Phenolics Extracted from Jasminum sambac Mitigates Diabetic Cardiomyopathy by Modulating Oxidative Stress, Apoptotic Mediators and the Nfr-2/HO-1 Pathway in Alloxan-Induced Diabetic Rats.

Phenolic acids extracted from leaves improved cardiac function and reduced complications of diabetes-induced cardiomyopathy in rats, suggesting potential therapeutic effects against diabetes-related heart problems.

Umar U et al (2023).

Molecules.

DOI:

10.3390/molecules28145453

PubMed:

37513325

Degradation Profiling of Nardosinone at High Temperature and in Simulated Gastric and Intestinal Fluids.

Xue BX et al (2023).

Molecules.

DOI:

10.3390/molecules28145382

PubMed:

37513256

Microfluidizing Technique Application for Algerian Cymbopogon citratus (DC.) Stapf Effects Enhanced Volatile Content, Antimicrobial, and Anti-Mycotoxigenic Properties.

The study found that microfluidization process enhanced the antimicrobial and anti-mycotoxigenic properties of Algerian lemongrass essential oil, making it more effective against bacteria, fungi, and mycotoxins.

Boudechicha A et al (2023).

Molecules.

DOI:

10.3390/molecules28145367

PubMed:

37513240

Cytotoxicity and Genotoxicity Evaluation of Zanthoxylum rhoifolium Lam and In Silico Studies of Its Alkaloids.

Azonsivo R et al (2023).

Molecules.

DOI:

10.3390/molecules28145336

PubMed:

37513210

Phytofabrication of Selenium Nanoparticles with Moringa oleifera (MO-SeNPs) and Exploring Its Antioxidant and Antidiabetic Potential.

This study synthesized selenium nanoparticles using a plant extract, which showed high purity, antioxidant properties (DPPH scavenging activity), and potential as an antidiabetic agent (inhibiting α-amylase and α-glucosidase enzymes). The plant extract could be a promising source for nanoparticle synthesis with biomedical applications.

Ahamad Tarmizi AA et al (2023).

Molecules.

DOI:

10.3390/molecules28145322

PubMed:

37513196