New biofunctional effects of oleanane-type triterpene saponins.

Various triterpene saponins have shown potential benefits in the gastrointestinal tract, affecting alcohol and glucose levels, gastric emptying, transit, and mucosal lesions, with shared modes of action.

Matsuda H et al (2023).

J Nat Med.

DOI:

10.1007/s11418-023-01730-w

PubMed:

37436646

Garlic essential oil ameliorates depression-like behaviors in unpredictable chronic mild stress by modulating the brain NLRP3 inflammasome pathway and influencing the gut barrier and microbiota.

Garlic essential oil reduces dopamine/serotonin turnover rates, reverses depression in rats, inhibits inflammation, and promotes intestinal barrier function, potentially influencing depression-like behavior.

Huang YJ et al (2023).

Food Funct.

DOI:

10.1039/d3fo00270e

PubMed:

37435927

Antimalarial and Antioxidant Activities of Ethanolic Stem Bark Extract of Terminalia macroptera in Swiss Albino Mice Infected with Plasmodium berghei.

Sidiki NNA et al (2023).

J Parasitol Res.

DOI:

10.1155/2023/3350293

PubMed:

37435530

NPLC0393 from Gynostemma pentaphyllum ameliorates Alzheimer's disease-like pathology in mice by targeting protein phosphatase magnesium-dependent 1A phosphatase.

Gynostemma pentaphyllum extract shows promise in reducing cognitive impairment in Alzheimer's disease. A specific compound from the extract, NPLC0393, targets a protein called PPM1A, reducing inflammation and tau hyperphosphorylation, and improving communication between microglia and neurons.

Lv J et al (2023).

Phytother Res.

DOI:

10.1002/ptr.7945

PubMed:

37434441

Anti-oxidant and Anti-inflammatory Effects of Ethanol Extract from Polygala sibirica L. var megalopha Fr. on Lipopolysaccharide-Stimulated RAW264.7 Cells.

Yang CL et al (2023).

Chin J Integr Med.

DOI:

10.1007/s11655-023-3602-7

PubMed:

37434032

Huangqin Decoction Delays Progress of Colitis-Associated Carcinogenesis by Regulating Nrf2/HO-1 Antioxidant Signal Pathway in Mice.

Gu LM et al (2024).

Chin J Integr Med.

DOI:

10.1007/s11655-023-3554-y

PubMed:

37434030

Comprehensive identification of glutathione peroxidase (GPX) gene family in response to abiotic stress in pepper (Capsicum annuum L.).

Wang W et al (2023).

Gene.

DOI:

10.1016/j.gene.2023.147625

PubMed:

37433355

The apiosyltransferase celery UGT94AX1 catalyzes the biosynthesis of the flavone glycoside apiin.

Yamashita M et al (2023).

Plant Physiol.

DOI:

10.1093/plphys/kiad402

PubMed:

37433052