Hypericum sampsonii exhibits anti-inflammatory activity in a lipopolysaccharide-induced sepsis mouse model.

Hsu YC et al (2023).

J Tradit Complement Med.

DOI:

10.1016/j.jtcme.2023.03.002

PubMed:

37396154

Antineoplastic Effects of Mucuna pruriens Against Human Colorectal Adenocarcinoma.

Seetharamaiah S et al (2023).

Appl Biochem Biotechnol.

DOI:

10.1007/s12010-023-04598-4

PubMed:

37395947

Metabolomics and Transcription Profiling of Pumpkin Fruit Reveals Enhanced Bioactive Flavonoids and Coumarins in Giant Pumpkin (Cucurbita maxima).

Chen C et al (2023).

J Agric Food Chem.

DOI:

10.1021/acs.jafc.3c01883

PubMed:

37395666

Phenolic composition, antioxidant, and cytotoxic effects on HeLa and HepG2 cancer cell lines of Mespilus germanica grown in Turkey.

In this study, researchers examined the antioxidant and cytotoxic properties of flavonoids and phenolic acids found in Turkish medlar. Using advanced analysis techniques, they identified various compounds in leaf and fruit extracts. Notably, the fruit extract showed excellent antioxidant properties, while the leaf extract demonstrated strong cytotoxicity against cancer cells. These findings suggest that Turkish medlar could be a valuable natural source for developing anticancer and antioxidant agents in the food and pharmaceutical industries.

Yunusa UM and Ozturk Urek R (2023).

Nat Prod Res.

DOI:

10.1080/14786419.2023.2230612

PubMed:

37395516

A Standardized Extract of Petasites hybridus L., Containing the Active Ingredients Petasins, Acts as a Pro-Oxidant and Triggers Apoptosis through Elevating of NF-κB in a Highly Invasive Human Breast Cancer Cell Line.

A Bulgarian butterbur root extract, rich in petasins, was tested for its anti-cancer properties on breast cancer cells and non-cancerous cells. The study investigated cell death, oxidative stress, and NF-κB signaling. This research is important as it highlights the anti-tumor potential of a traditional medicinal plant, providing insights into possible future treatments for breast cancer.

Apostolova S et al (2023).

Front Biosci (Landmark Ed).

DOI:

10.31083/j.fbl2806111

PubMed:

37395030

Protective effect of Arum maculatum against dextran sulfate sodium induced colitis in rats.

Doğan GT et al (2023).

Biotech Histochem.

DOI:

10.1080/10520295.2023.2225226

PubMed:

37394993

Deacetyl epoxyazadiradione ameliorates BPA-induced neurotoxicity by mitigating ROS and inflammatory markers in N9 cells and zebrafish larvae.

A study investigates the potential protective effects of a neem-derived compound, DEA, against the harmful effects of BPA exposure. DEA reduced cell damage in N9 cells and improved antioxidant production in zebrafish larvae, suggesting its ability to mitigate oxidative stress and inflammation caused by BPA.

Murugan R et al (2023).

Comp Biochem Physiol C Toxicol Pharmacol.

DOI:

10.1016/j.cbpc.2023.109692

PubMed:

37394128

Novel pH-responsive E-selectin targeting natural polysaccharides hybrid micelles for diabetic nephropathy.

Researchers developed hybrid micelles loaded with Puerarin to treat diabetic nephropathy by targeting inflammatory and oxidative stress reactions in the kidney. promising strategy using natural polysaccharides.

Guo C et al (2023).

Nanomedicine.

DOI:

10.1016/j.nano.2023.102696

PubMed:

37394108