Cancer Studies

Evaluation of the Anticancer, Antidiabetic, and In vitro Wound Healing Properties of the Aqueous and Ethanolic Extract of Hibiscus rosa-sinensis L.

Study investigated therapeutic potential of plant extract for cancer, diabetes, and wound healing. Extract showed promising anticancer, antidiabetic, and wound healing activities. Contains key bioactive compounds. Could lead to new herbal treatments.

Harini VS et al (2024).
J Pharm Bioallied Sci.
PubMed:
38882727

In Silico Analysis of Selective Bioactive Compounds from Acronychia Pedunculata as a Potential Inhibitor of HER2 in Colorectal Cancer.

Researchers studied compounds from Acronychia pedunculata for potential inhibition of HER2 in colorectal cancer. 12 compounds showed promising properties for drug-likeness and oral bioavailability, with two compounds showing strong binding affinities to HER2. Further experimental validation is needed.

Ramya S et al (2024).
J Pharm Bioallied Sci.
PubMed:
38882725

Natural Prenylflavones from the Stem Bark of Artocarpus altilis: Promising Anticancer Agents for Oral Squamous Cell Carcinoma Targeting the Akt/mTOR/STAT-3 Signaling Pathway.

Extracted compounds from Parkinson Fosberg bark showed promising cytotoxic effects on oral cancer cells by modulating protein expression and signaling pathways. Potential avenue for effective oral cancer management.

Aswathy M et al (2024).
ACS Omega.
PubMed:
38882137

Cynanchum paniculatum (Bunge) Kitag. ex H.Hara inhibits pancreatic cancer progression by inducing caspase-dependent apoptosis and suppressing TGF-β-mediated epithelial-mesenchymal transition.

Study explores potential anti-cancer effects of (Bunge) Kitag. ex H.Hara in pancreatic cancer. CPAE inhibits proliferation, induces apoptosis, and suppresses metastasis. Promising herbal medicine for pancreatic cancer treatment.

Cheng CS et al (2024).
Front Pharmacol.
PubMed:
38881872

Mechanism of 5-fluorouracil induced resistance and role of piperine and curcumin as chemo-sensitizers in colon cancer.

Researchers studied chemoresistance in colorectal cancer cells treated with 5-FU, finding various resistance mechanisms. Curcumin and piperine enhance 5-FU sensitivity, showing promise for improving chemotherapy effectiveness.

Bhattacharjya D and Sivalingam N (2024).
Naunyn Schmiedebergs Arch Pharmacol.
PubMed:
38878089

Nimbolide: A Potential Phytochemical Agent in Multimodal Pancreatic Cancer Therapies.

Researchers are looking into the use of the phytochemical nimbolide (found in Azadirachta indica) as a potential treatment for pancreatic cancer. Nimbolide has shown promising anticancer properties in preclinical studies, but further research is needed to determine its safety and effectiveness in human trials.

Jogi M et al (2024).
Mini Rev Med Chem.
PubMed:
38874049

Current Evidence on Molecular Mechanisms of Andrographolide in Cancer.

Andrographolide, a natural compound from Andrographis paniculata, shows promising anti-cancer properties, inhibiting multiple signaling pathways and causing anti-proliferative and apoptotic effects. It has no side effects and potential as a new cancer treatment, but more research is needed for full understanding and clinical application.

Attri DC et al (2024).
Curr Med Chem.
PubMed:
38867528

Green synthesis of zinc oxide nanoparticles using Rhus coriaria extract and their anticancer activity against triple-negative breast cancer cells.

Plant-extracted ZnO NPs show potential as eco-friendly cancer treatment. Biosynthesized by Rhus coriaria fruit extract, they exhibit anti-tumor effects and induce apoptosis in breast cancer cells. Exciting implications for cancer nanotechnology.

Mongy Y and Shalaby T (2024).
Sci Rep.
PubMed:
38866790