Ethanolic extract of Euphorbia royleana Boiss. reduces metastasis of breast cancer cells and inhibits tumor progression in vivo.

ERA treatment reduces BC metastasis and progression by down-regulating key markers and angiogenic chemokines, inhibiting tumor growth in mice. ERA extract contains potential therapeutic compounds to combat BC.

Gull S et al (2024).

Med Oncol.

DOI:

10.1007/s12032-024-02378-6

PubMed:

38743193

Codonopsis pilosula-derived glycopeptide dCP1 promotes the polarization of tumor-associated macrophage from M2-like to M1 phenotype.

Glycopeptide dCP1 from Codonopsis pilosula extracts can convert tumor-promoting M2-like tumor-associated macrophages (TAM) into tumor-suppressive M1 phenotype, potential for tumor treatment.

Liu H, Yao M and Ren J (2024).

Cancer Immunol Immunother.

DOI:

10.1007/s00262-024-03694-6

PubMed:

38743074

Anti-Metastatic Effects of Standardized Polysaccharide Fraction from Diospyros kaki Leaves via GSK3β/β-Catenin and JNK Inactivation in Human Colon Cancer Cells.

Polysaccharide from PLE0 leaves inhibits colon cancer metastasis by reducing cell migration and invasion, suppressing N-cadherin and vimentin expression, upregulating E-cadherin, and inhibiting MMP-2/9 through GSK3β/β-catenin and JNK signaling pathways. This research may lead to potential treatments for colon cancer.

Lee WS et al (2024).

Polymers (Basel).

DOI:

10.3390/polym16091275

PubMed:

38732748

Berberis vulgaris L. Root Extract as a Multi-Target Chemopreventive Agent against Colon Cancer Causing Apoptosis in Human Colon Adenocarcinoma Cell Lines.

BVR root extract from L. () showed promising chemopreventive effects against colon cancer cells, inducing programmed cell death and altering gene expression related to apoptosis. BVR also demonstrated antioxidant and anti-inflammatory properties. Consider using BVR as a comprehensive chemopreventive agent in colorectal cancer.

Och A et al (2024).

Int J Mol Sci.

DOI:

10.3390/ijms25094786

PubMed:

38732003

An In Vitro Study on the Cytotoxic, Antioxidant, and Antimicrobial Properties of Yamogenin-A Plant Steroidal Saponin and Evaluation of Its Mechanism of Action in Gastric Cancer Cells.

Yamogenin from plants has strong cytotoxic effects on gastric cancer cells, induces apoptosis via multiple pathways, and has moderate antioxidant properties. It may be a promising option for treating and preventing gastric cancers.

Stefanowicz-Hajduk J et al (2024).

Int J Mol Sci.

DOI:

10.3390/ijms25094627

PubMed:

38731847

Splenic Elemental Composition of Breast Cancer-Suffering Rats Supplemented with Pomegranate Seed Oil and Bitter Melon Extract.

Białek M et al (2024).

Molecules.

DOI:

10.3390/molecules29091942

PubMed:

38731433

Oroxylin A suppresses breast cancer-induced osteoclastogenesis and osteolysis as a natural RON inhibitor.

Chen Y et al (2024).

Phytomedicine.

DOI:

10.1016/j.phymed.2024.155688

PubMed:

38728920

SIRT1-activating butein inhibits arecoline-induced mitochondrial dysfunction through PGC1α and MTP18 in oral cancer.

Behera BP et al (2024).

Phytomedicine.

DOI:

10.1016/j.phymed.2024.155511

PubMed:

38723523