Cancer Studies

A Water Polysaccharide-Protein Complex from Grifola frondosa Inhibit the Growth of Subcutaneous but Not Peritoneal Colon Tumor under Fasting Condition.

Grifola frondosa boosts immune system, triggers cell death in cancer. Further research needed on its potential in slowing tumor growth with nutrient restriction.

Xu Y et al (2024).
Mol Nutr Food Res.
PubMed:
38924315

Construction of a Synergy Combination Model for Turmeric (Curcuma longa L.) and Black Pepper (Piper nigrum L.) Extracts: Enhanced Anticancer Activity against A549 and NCI-H292 Human Lung Cancer Cells.

Turmeric and black pepper extracts have a synergistic effect on lung cancer cells, potentially reducing side effects of synthetic drugs. Further research is needed to understand specific mechanisms.

Cho HK, Park CG and Lim HB (2024).
Curr Issues Mol Biol.
PubMed:
38921003

Folate-Modified Curcumin-Loaded Nanoparticles for Overcoming Delivery Challenges in Cancer Treatment: A Narrative Review.

Folate-modified curcumin nanoparticles show promise in targeting cancer cells with higher efficacy and lower toxicity, based on preclinical studies. Clinical trials needed for confirmation.

Nosrati-Oskouie M et al (2024).
Curr Pharm Biotechnol.
PubMed:
38918979

5-fluorouracil and Rumex obtusifolius extract combination trigger A549 cancer cell apoptosis: uncovering PI3K/Akt inhibition by in vitro and in silico approaches.

Study examined the anticancer effects of Rumex obtusifolius (RO) extract and 5-fluorouracil (5-FU) on lung cancer cells. Results show reduced inflammation, increased apoptosis, and potential therapeutic benefits with minimal side effects.

Ginovyan M et al (2024).
Sci Rep.
PubMed:
38918540

Chemical compounds, anti-tumor and anti-neuropathic pain effect of hemp essential oil in vivo.

Study extracted and analyzed hemp essential oil (HEO) components, showing potential anti-tumor and anti-neuropathic pain effects. HEO reduced inflammatory cytokines and inhibited tumor growth in mice models, suggesting potential in cancer treatment and medicinal development of hemp.

Xu Y et al (2024).
Fitoterapia.
PubMed:
38914272

Bletilla striata polysaccharide-coated andrographolide nanomicelles for targeted drug delivery to enhance anti-colon cancer efficacy.

Researchers used a polysaccharide-vitamin E succinate polymer to improve tumor targeting and anti-colon cancer effects of andrographolide. This novel delivery system shows promise for cancer treatment.

Yue Z et al (2024).
Front Immunol.
PubMed:
38911867

Research progress on anti-tumor mechanisms of scutellarin.

Scutellarin, a flavonoid, shows promising anti-tumor effects by inhibiting growth/metastasis, inducing apoptosis/autophagy, and enhancing sensitivity to chemotherapy. Further research can explore its potential in cancer treatment.

Ge HC and Zhong XH (2024).
J Asian Nat Prod Res.
PubMed:
38910315