Coconut kernel extract (CKE) prevented skin tumor growth in mice by reducing oxidative stress and suppressing c-MYC overexpression. CKE showed higher antioxidant activity than ascorbic acid, making it a potential dietary antioxidant with anti-tumor properties.
Brusatol from Brucea javanica inhibits bladder cancer growth by inducing ferroptosis through the Chac1/Nrf2/SLC7A11 pathway, showing promise as a potential antineoplastic drug.
Noni juice may prevent cancer by stopping harmful chemicals from damaging DNA. In a study, noni juice was found to have anti-tumor effects when used with a chemotherapy drug.
Vitekwangin B shows promise in inhibiting ANO1 protein levels in prostate cancer and NSCLC cells, potentially offering a new therapy option with minimal toxicity and resistance issues. More research needed.
Researchers isolated new cassane diterpenoids from Caesalpinia sappan seeds. Compound 4 showed anti-cancer activity against pancreatic cancer cells by inducing autophagy through the ROS/AMPK/mTORC1 pathway. This suggests potential for 4 as a therapy for pancreatic cancer.
Arnicolide D from Centipeda minima shows promising anticancer effects by inhibiting cell proliferation, inducing apoptosis, and suppressing metastasis. It targets key signaling pathways and displays broad-spectrum cytotoxicity, warranting further investigation for potential clinical use.
Isorhamnetin (ISO) is a natural compound with antitumor, anti-inflammatory, and organ-protective properties. It is cost-effective, widely available, and shows minimal side effects. Research highlights ISO's potential for new drug development and various health benefits.
Researchers computationally investigated phytochemicals in plant for breast cancer treatment. Isovitexin, vitexin, rosmarinic acid, nepetoidin A, and luteolin show strong anti-cancer properties with good safety profiles for oral administration. Important for developing potential breast cancer treatments.