Brusatol (BT), from a Chinese herb, shows promising anti-cancer and anti-inflammatory properties. This review highlights its potential for treating various diseases, including leukemia and malaria.
Polyphenols extracted from Korean L. enhance the anticancer effect of DTX in HCT116 cells by regulating p53 and other signaling pathways, leading to increased apoptotic cell death. This could improve DTX-containing chemotherapy for cancers with wild-type p53.
BCP80-2 polysaccharide from Belamcanda chinensis inhibits tumor growth, metastasis, and angiogenesis in zebrafish. It suppresses cell migration via FAK pathway and boosts immune response.
Scientists discovered new compounds from Typha angustifolia pollen with potential anti-cancer properties. These compounds induce cell death, arrest cell cycle, and inhibit migration & invasion in breast cancer cells by activating the TGF-β1 signaling pathway. Animal studies also showed promising anti-breast cancer activity.
Researchers screened Middle Eastern plants for cytotoxic effects against lung cancer cell lines. Some extracts showed potent efficacy in inducing apoptosis in cancer cells, suggesting potential as alternative cancer treatments. Additional research into these plant extracts could lead to new cancer therapies.
Researchers optimized ethanol extraction process of Lour/Sharen, identifying 35 bioactive compounds with antioxidant and antitumor properties. Ethyl acetate fraction showed highest content and activity, suggesting potential industrial applications.
Researchers isolated 14 sesquiterpenes from Youngia japonica. One, labeled "2," showed strong cytotoxic activity against A549 lung cancer cells by increasing ROS levels, inducing apoptosis, and enhancing cleaved caspase 3 expression. This compound has potential for lung cancer treatment.