Cancer Studies

Unveiling the therapeutic potential of thymol from Nigella sativa L. seed: selective anticancer action against human breast cancer cells (MCF-7) through down-regulation of Cyclin D1 and proliferative cell nuclear antigen (PCNA) expressions.

Thymol derived from Nigella sativa can potentially inhibit the growth of breast cancer cells by suppressing the expression of key genes involved in cell proliferation.

Vahitha V et al (2024).
Mol Biol Rep.
PubMed:
38170326

Polysaccharide isolated from Grifola frondosa eliminates myeloid-derived suppressor cells and inhibits tumor growth by enhancing T cells responses.

extracted from effectively suppresses breast tumor growth in mice by reducing the accumulation of MDSCs, which promote tumor growth. It also restores and activates CD8T cells, enhancing the antitumor immune response. Promising therapeutic agent for breast cancer.

Li X et al (2024).
Int J Biol Sci.
PubMed:
38169590

Baicalin Induces Gastric Cancer Cell Pyroptosis through the NF-κB-NLRP3 Signaling Axis.

Baicalein, a component in traditional Chinese medicine, induces pyroptosis in gastric cancer cells through the NF-κB-NLRP3 signaling axis. This could be an effective and novel therapeutic approach for treating gastric cancer, providing hope for improved outcomes.

Liu J et al (2024).
J Cancer.
PubMed:
38169542

Anticancer activity of Curcuma aeroginosa essential oil and its nano-formulations: cytotoxicity, apoptosis and cell migration effects.

This study investigates the anticancer activity of Curcuma aeruginosa essential oil and its nano-formulations. Curcuma aeruginosa has potential in treating diseases and has various properties such as anti-HIV, hepatoprotective, antimicrobial, and anti-androgenic activities. Understanding its anticancer activity could have implications for cancer treatment.

Panyajai P et al (2024).
BMC Complement Med Ther.
PubMed:
38166788

Folic Acid-Conjugated Chitosan-Coated Solid Lipid Nanoparticles: Precision Targeting of Artemisia vulgaris Essential Oils for Anticancer Therapy.

Nanoparticles loaded with Artemisia vulgaris oil showed strong potential in cancer therapy due to their drug delivery capabilities, antitumor and antibacterial properties, and ability to scavenge free radicals.

Aghabagherzadeh M, Karimi E and Zareian M (2024).
Chem Biodivers.
PubMed:
38164058

Nicotine promotes epithelial to mesenchymal transition and gemcitabine resistance via hENT1/RRM1 signalling in pancreatic cancer and chemosensitizing effects of Embelin-a naturally occurring benzoquinone.

Prashanth N et al (2024).
Sci Total Environ.
PubMed:
38163613

Biogenic Zinc oxide nanoparticles from Celosia argentea: toward improved antioxidant, antibacterial, and anticancer activities.

Researchers synthesized zinc oxide nanoparticles using a plant extract. The nanoparticles had antioxidant, antibacterial, and anticancer properties, inducing cell death through oxidative stress. Further study on the impact of green synthesis is suggested.

Alghamdi RA et al (2023).
Front Bioeng Biotechnol.
PubMed:
38162186