Cancer Studies

Corrigendum to "Essential oils from Inula japonica and Angelicae dahuricae enhance sensitivity of MCF-7/ADR breast cancer cells to doxorubicin via multiple mechanisms" [J. Ethnopharmacol. 180 (2016) 18-27].

Wu M et al (2023).
J Ethnopharmacol.
PubMed:
38008656

In Vitro Anti-Tumor and Hypoglycemic Effects of Total Flavonoids from Willow Buds.

Willow bud flavonoids showed anti-tumor effects on cervical, colon, and breast cancer cells and displayed hypoglycemic properties, indicating potential applications in food and pharmaceutical industries.

Zhang P et al (2023).
Molecules.
PubMed:
38005279

Total Flavonoids in Artemisia absinthium L. and Evaluation of Its Anticancer Activity.

The study used ultrasound-assisted enzymatic hydrolysis to improve the yield of flavonoids in L. They identified Cynaroside and Astragalin as potential anticancer compounds that inhibit cervical cancer growth by regulating signaling proteins. These compounds also induce apoptosis by increasing ROS levels.

He M et al (2023).
Int J Mol Sci.
PubMed:
38003540

Adjuvant Effect of Cinnamon Polyphenolic Components in Colorectal Cancer Cell Lines.

Cinnamon extracts, when co-administered with the anticancer drug cetuximab, reduce the required drug dose for colorectal cancer treatment. These extracts induce apoptosis in cancer cells and may be used as adjuvants to minimize side effects of the drug.

Palmioli A et al (2023).
Int J Mol Sci.
PubMed:
38003308

New Megastigmane and Polyphenolic Components of Henna Leaves and Their Tumor-Specific Cytotoxicity on Human Oral Squamous Carcinoma Cell Lines.

Researchers found a new compound () in henna, along with other known compounds. They also discovered new ellagitannins that are cytotoxic to oral squamous cell carcinoma cells. Henna has potential for anti-oral cancer treatment and further study is encouraged.

Orabi MAA et al (2023).
Antioxidants (Basel).
PubMed:
38001804

Hydroxytyrosol Counteracts Triple Negative Breast Cancer Cell Dissemination via Its Copper Complexing Properties.

Polyphenols can bind to copper, a metal involved in cancer progression. Hydroxytyrosol, a metabolite of oleuropein, reduces copper levels and inhibits the metastatic potential of triple-negative breast cancer cells by modulating key signaling pathways. This highlights the therapeutic potential of polyphenols in cancer treatment.

Perta N et al (2023).
Biology (Basel).
PubMed:
37998036

Prenylated chromones and flavonoids isolated from the roots of Flemingia macrophylla and their anti-lung cancer activity.

Researchers investigated prenylated flavonoids in Flemingia macrophylla, which regulate the p53 protein. The study aims to identify these compounds, evaluate their activity, establish their structure-activity relationship, and understand their mechanisms. This research can provide potential candidates for the development of antitumor drugs.

Wang B et al (2023).
Chin Med.
PubMed:
37996917

Adverse effect of Tamarindus indica and tamoxifen combination on redox balance and genotoxicity of breast cancer cell.

Researchers studied the effects of Tamarindus indica extract and tamoxifen (TAM) on breast cancer cells. The study confirmed that phenolic compounds have anticancer actions and using them in combination with TAM may enhance treatment outcomes. This information is significant for improving therapeutic efficacy in breast cancer treatment.

Guneidy RA et al (2023).
J Genet Eng Biotechnol.
PubMed:
37987952