Euphorbia factor L2 suppresses the generation of liver metastatic ascites in breast cancer via inhibiting NLRP3 inflammasome activation.

Jiang D et al (2024).

Int J Mol Med.

DOI:

10.3892/ijmm.2023.5332

PubMed:

38063231

Baicalin and baicalein in modulating tumor microenvironment for cancer treatment: A comprehensive review with future perspectives.

Baicalin and baicalein, derived from a Chinese medicinal plant, have low toxicity to normal cells and exhibit anticancer activities. They regulate tumor microenvironmental cells and extracellular matrix, inhibiting tumor angiogenesis, progression, and metastasis. Further research is needed to improve their bioavailability and clinical applications.

Wang R et al (2023).

Pharmacol Res.

DOI:

10.1016/j.phrs.2023.107032

PubMed:

38061594

Sulfated polysaccharides of Laetiporus sulphureus fruiting bodies exhibit anti-breast cancer activity through cell cycle arrest, apoptosis induction, and inhibiting cell migration.

This study investigated the difference between polysaccharides (PS) and sulfated polysaccharides (SPS) in Laetiporus sulphureus mushrooms. SPS have not been previously reported in mushrooms. Understanding these differences could contribute to identifying potential anti-breast cancer agents.

Jen CI et al (2023).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117546

PubMed:

38061441

Brucea Javanica Oil Emulsion Injection inhibits proliferation of pancreatic cancer via regulating apoptosis-related genes.

This study investigated the anti-tumor effects of Brucea Javanica Oil Emulsion Injection (BJOEI) on pancreatic cancer. They found that BJOEI inhibited tumor growth and induced cell apoptosis by regulating apoptosis-related genes, particularly PPARG. BJOEI may have potential therapeutic effects for pancreatic cancer.

Wu Y et al (2023).

Am J Cancer Res.

PubMed:

38058798

Tannins in Phyllanthus emblica L. improves cisplatin efficacy in lung cancer cells by boosting endoplasmic reticulum stress to trigger immunogenic cell death.

Tannins in Phyllanthus emblica L. (PTF) can inhibit tumor growth and have cytotoxic effects on lung cancer cells in vitro. This suggests PTF may be a potential immunotherapy for lung cancer treatment.

Hu Q et al (2023).

Phytomedicine.

DOI:

10.1016/j.phymed.2023.155219

PubMed:

38056150

Alkaline lignins from Morinda citrifolia leaves are potential immunomodulatory, antitumor, and antimicrobial agents.

This study investigated the immunomodulatory, antitumor, and antimicrobial activities of lignin from Morinda citrifolia leaves. The results suggest that this lignin can activate immune cells, produce anti-inflammatory factors, and inhibit tumor and microbial growth. It has potential for developing biomedical and pharmaceutical products.

Cruz Filho IJ et al (2023).

An Acad Bras Cienc.

DOI:

10.1590/0001-3765202320221026

PubMed:

38055562

Capturing Sialyl-glycan on Live Cancer Cells by Tailored Boronopeptide.

Scientists used a boronic acid probe to enhance the binding ability of the WGA peptide to sialic acid. This improved binding could be used to profile sialyl-glycan on cancer cells, offering potential benefits over current methods.

Chatterjee S et al (2023).

Chemistry.

DOI:

10.1002/chem.202303327

PubMed:

38051420

Diosbulbin C, a novel active ingredient in Dioscorea bulbifera L. extract, inhibits lung cancer cell proliferation by inducing G0/G1 phase cell cycle arrest.

Scientists discovered that diosbulbin C, a natural compound found in traditional Chinese medicine, has strong anti-cancer properties against non-small cell lung cancer. This finding is important for developing new therapeutic interventions for the disease.

Zhu Z et al (2023).

BMC Complement Med Ther.

DOI:

10.1186/s12906-023-04245-9

PubMed:

38049779