Cancer Studies

Viscum album, as alternative and bridge to palliative chemotherapy in recurrent gallbladder cancer following laparoscopic radical cholecystectomy: a case report.

A 78-year-old woman with gallbladder cancer refused further chemotherapy after recurrence. She started Viscum album therapy, which decreased metastases and reduced CA19-9 levels. This therapy could be a bridge to palliative chemotherapy for patients unable to undergo standard treatment for recurrent gallbladder cancer.

Shin J, Yim E and Kang CM (2023).
Korean J Clin Oncol.
PubMed:
38229495

Targeted inhibition of the HNF1A/SHH axis by triptolide overcomes paclitaxel resistance in non-small cell lung cancer.

Triptolide, a compound from Tripterygium wilfordii Hook F, enhances the effectiveness of paclitaxel in treating paclitaxel-resistant lung cancer cells by inhibiting the HNF1A/SHH/ABCB1 pathway. This study suggests potential use of triptolide as a therapy for patients with paclitaxel resistance.

Li LB et al (2024).
Acta Pharmacol Sin.
PubMed:
38228910

Co-treatment of silymarin and cisplatin inhibited cell proliferation, induced apoptosis in ovarian cancer.

Researchers investigated the effects of combining cisplatin (a chemotherapy drug) with silymarin (an extract from milk thistle) on ovarian cancer cells. Silymarin enhanced the anticancer effects of cisplatin, offering potential for improved treatment options. Important for developing effective ovarian cancer therapies.

Karimzadeh MR et al (2024).
Mol Biol Rep.
PubMed:
38227082

Pharmacodynamic components and mechanisms of ginger (Zingiber officinale) in the prevention and treatment of colorectal cancer.

Ginger has many beneficial properties like anti-inflammatory, antioxidant, and anticancer effects. It has a strong history in treating intestinal diseases and shows promise for preventing and treating colorectal cancer.

Xiang S et al (2024).
J Ethnopharmacol.
PubMed:
38218504

Discovery of bi-4-methoxycarbonyl-2-quinolone and evaluation of its anti-inflammatory and anti-cancer activity in vitro.

A new alkaloid compound with anti-inflammatory and anti-cancer properties was discovered, along with six known alkaloids, holding promise for potential therapeutic applications in inflammation and cancer treatment.

Wang W et al (2024).
Nat Prod Res.
PubMed:
38217490

Caffeic acid 3,4-dihydroxyphenethyl ester prevents colorectal cancer through inhibition of multiple cancer-promoting signal pathways in 1,2-Dimethylhydrazine/dextran sodium sulphate mouse model.

Researchers studied the molecule CADPE and its potential to prevent colorectal cancer in a mouse model induced by the use of DMH and DSS. Results could contribute to future cancer prevention strategies.

Tao J et al (2024).
J Tradit Chin Med.
PubMed:
38213241

Efficacy and safety of traditional plant-based medicines for preventing chronic oxaliplatin-induced peripheral neurotoxicity in patients with colorectal cancer: A systematic review and meta-analysis with core herb contribution.

Researchers studied the use of traditional plant-based medicines to prevent nerve damage caused by chemotherapy. Results are unclear due to different medicine combinations and lack of understanding of their mechanisms.

Han J et al (2024).
J Ethnopharmacol.
PubMed:
38211824