Cancer Studies

Identification of apposite antagonist for androgen receptor in prostate cancer: an in silico study of fenugreek compounds.

Fenugreek compounds were tested for their potential as anti-cancer agents on benign prostate cancer by targeting the androgen receptor. The compounds chlorogenic acid and kaempferol showed the most promise, indicating their potential for drug development in BPC treatment. (25 words)

CancerEndocrinology Trigonella foenum
Olugbogi EA et al (2023).
J Biomol Struct Dyn.
DOI:
10.1080/07391102.2023.2273988
PubMed:
37897191

Obtaining New Candidate Peptides for Biological Anticancer Drugs from Enzymatic Hydrolysis of Human and Bovine Hemoglobin.

Hydrolyzing hemoglobin produces bioactive peptides with anticancer properties. Certain bovine hemoglobin peptides are more active than human peptides, suggesting potential for anticancer drug development using hemoglobin.

Cancer Lepidium sativum
Outman A et al (2023).
Int J Mol Sci.
DOI:
10.3390/ijms242015383
PubMed:
37895063

Chemical Composition, Functional and Anticancer Properties of Carrot.

Carrots (L.) have bioactive compounds with health benefits. Edible carrot root is rich in carotenoids and fiber, while wild carrot has been used for gastric ulcer and diabetes. This review explores the chemical composition and potential anticancer properties of both subspecies. Useful for cancer treatment research.

Cancer Daucus carota
Mandrich L et al (2023).
Molecules.
DOI:
10.3390/molecules28207161
PubMed:
37894640

Chlorahololide D, a Lindenane-Type Sesquiterpenoid Dimer from Chloranthus holostegius Suppressing Breast Cancer Progression.

Chlorahololide D, a compound found in plants, has potential as an anti-breast cancer drug. It blocks cell growth, triggers apoptosis, inhibits cell migration, and has anti-angiogenesis effects. More studies are needed to confirm its efficacy.

Cancer Chloranthus holostegius
Li Y et al (2023).
Molecules.
DOI:
10.3390/molecules28207070
PubMed:
37894550

Cytotoxic and Antitumor Effects of the Hydroalcoholic Extract of Tagetes erecta in Lung Cancer Cells.

Plant extract shows potential as a therapeutic option for lung cancer, with cytotoxic effects on tumor cells, reduced tumor growth, and improved chemotherapy effectiveness.

Cancer Tagetes erecta
González ASC et al (2023).
Molecules.
DOI:
10.3390/molecules28207055
PubMed:
37894532

The anticancer and antibacterial potential of bioactive secondary metabolites derived From bacterial endophytes in association with Artemisia absinthium.

Researchers explored the diversity of bacteria in the medicinal plant A. absinthium and discovered that P. aeruginosa SD01 has potent antimicrobial and anticancer properties, specifically against S. aureus and MRSA. This study identified several bioactive secondary metabolites that could be used in drug discovery.

Cancer Artemisia absinthium
Damavandi MS, Shojaei H and Esfahani BN (2023).
Sci Rep.
DOI:
10.1038/s41598-023-45910-w
PubMed:
37891400

Effects of Origanum majorana on Breast Cancer Cells: An Alternative to Chemotherapy?

Study examined the effects of marjoram extracts on breast cancer cells and normal breast tissue cells. Marjoram extracts showed cytotoxic effect on cancer cells and no major effects on normal cells. This suggests marjoram extracts could be a promising alternative to chemotherapy for breast cancer treatment.

Cancer Origanum majorana
Sanders Z et al (2023).
Metabolites.
DOI:
10.3390/metabo13101083
PubMed:
37887408

In silico and in vitro study of bioactive compounds of Nigella sativa for targeting neuropilins in breast cancer.

Researchers analyzed leaves for potential anti-cancer treatments, finding they targeted angiogenesis and neuropilins in breast cancer. In-silico analysis confirmed stability of Neuropilin complexes.

Cancer Nigella sativa
Zafar I et al (2023).
Front Chem.
DOI:
10.3389/fchem.2023.1273149
PubMed:
37885828
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