Alkaloids from the roots of Sophora flavescens and their anti-tumor activity.

This study analyzed Sophora flavescens roots and identified new and known alkaloids. Compound 12 showed inhibitory effects on MCF-7 cell growth, making it a potential anti-tumor agent targeting human Rho GTPase activating protein 5 variant and human arachidonate 12-lipoxygenase (12S-type).

Xu Y et al (2023).

Fitoterapia.

DOI:

10.1016/j.fitote.2023.105685

PubMed:

37743030

The role of Ginkgo Folium on antitumor: Bioactive constituents and the potential mechanism.

Hu D et al (2024).

J Ethnopharmacol.

DOI:

10.1016/j.jep.2023.117202

PubMed:

37742878

Kaempferol promotes non-small cell lung cancer cell autophagy via restricting Met pathway.

Kaempferol, extracted from Hedyotis diffusa, has been found to have anti-cancer effects on non-small cell lung cancer cells. Further research is needed to understand the underlying mechanisms.

Wang R et al (2023).

Phytomedicine.

DOI:

10.1016/j.phymed.2023.155090

PubMed:

37738907

Pharmacological Activity of Matrine in Inhibiting Colon Cancer Cells VM Formation, Proliferation, and Invasion by Downregulating Claudin-9 Mediated EMT Process and MAPK Signaling Pathway.

Matrine, a compound in Chinese herbal plant, has shown promising anticancer effects on colon cancer. This study investigates how Matrine works and its potential as a therapy for colon cancer.

Du Q et al (2023).

Drug Des Devel Ther.

DOI:

10.2147/DDDT.S417077

PubMed:

37719361

Potential anti-cancer activity of Moringa oleifera derived bio-active compounds targeting hypoxia-inducible factor-1 alpha in breast cancer.

Researchers have found that a protein called HIF-1α plays a crucial role in breast cancer spread. Inhibiting HIF-1α can have anti-cancer effects and improve cancer therapy. Phytochemicals from the 'Tree of Life' plant have shown potential in modulating HIF and treating breast cancer.

Masarkar N et al (2023).

J Complement Integr Med.

DOI:

10.1515/jcim-2023-0182

PubMed:

37712721

Green synthesis of silver nanoparticles using Morinda citrifolia Linn leaf extract and its antioxidant, antibacterial and anticancer potential.

Nanomedicine is a promising approach for treating both infectious and non-infectious diseases, potentially revolutionizing medicine.

Datkhile KD et al (2023).

Pharm Nanotechnol.

DOI:

10.2174/2211738511666230913095001

PubMed:

37711107

Hedyotis Diffusa-Scutellaria Barbata inhibits Breast Cancer Ethyl Acetate Fraction from Hedyotis Diffusa Plus Scutellaria Barbata inhibits the Progression of Breast Cancer via Targeting LMO1 and AKT/Mtor Signaling Pathway.

Scutellaria barbata and Hedyotis diffusa herb pair (SH) has anticancer effects in various cancers, including breast cancer, but the precise mechanism is unknown.

Li Z et al (2023).

Comb Chem High Throughput Screen.

DOI:

10.2174/1386207326666230913105858

PubMed:

37711008

High-throughput sequencing reveals Jatrorrhizine inhibits colorectal cancer growth by ferroptosis-related genes.

Huang L et al (2023).

BMC Med Genomics.

DOI:

10.1186/s12920-023-01619-3

PubMed:

37710311