Plumbagin induces apoptosis, cell cycle arrest, and inhibits protein synthesis in LoVo colon cancer cells: A proteomic analysis.

Plumbagin, extracted from Plumbago zeylanica L., inhibits growth and induces apoptosis in LoVo colon cancer cells. Mechanisms include cell cycle arrest and disruption of protein synthesis. Potential therapeutic for colon cancer.

Shu J et al (2023).

Chem Biol Drug Des.

DOI:

10.1111/cbdd.14305

PubMed:

37558615

The Action Mechanisms, Anti-Cancer and Antibiotic-Modulation Potential of Vaccinium myrtillus L. Extract.

The study explored the antimicrobial and anticancer properties of extracts from bilberry leaves and stems. These extracts contain high levels of beneficial compounds.

Ginovyan M et al (2023).

Discov Med.

DOI:

10.24976/Discov.Med.202335177.59

PubMed:

37553312

Out-of-set association analysis of lung cancer drugs and symptoms based on clinical case data mining.

Lung cancer is a significant global health issue, resulting in a high number of deaths. It is particularly prevalent in China, requiring attention for prevention and treatment strategies.

Hong M et al (2023).

Technol Health Care.

DOI:

10.3233/THC-230269

PubMed:

37545275

Mangiferin is a new potential antimalarial and anticancer drug for targeting serine hydroxymethyltransferase.

Mangiferin, a compound found in mango leaves, inhibits an enzyme involved in the production of DNA building blocks. This discovery could lead to the development of new antimalarial and anticancer drugs.

Maenpuen S et al (2023).

Arch Biochem Biophys.

DOI:

10.1016/j.abb.2023.109712

PubMed:

37543353

Anti-proliferative potentials of Aconitum heterophyllum Root Extract in Human Breast cancer (MDA-MB-231) cell lines-Genetic and Antioxidant enzyme approach.

The study evaluated the anticancer effects of plant components on breast cancer cells. It found changes in gene expression that may be relevant to tumorigenesis and cell death. The use of Phyto-Niosomes showed mixed results compared to ethanolic root extract.

Saravanan S, Hari R and Sekar K (2023).

Avicenna J Med Biotechnol.

DOI:

10.18502/ajmb.v15i3.12929

PubMed:

37538242

Multitargeted pharmacokinetics, molecular docking and network pharmacology-based identification of effective phytocompounds from Sauropus androgynus (L.) Merr for inflammation and cancer treatment.

Gayathiri E et al (2023).

J Biomol Struct Dyn.

DOI:

10.1080/07391102.2023.2243335

PubMed:

37534448

Xanthohumol hinders invasion and cell cycle progression in cancer cells through targeting MMP2, MMP9, FAK and P53 genes in three-dimensional breast and lung cancer cells culture.

Xanthohumol (XN) is a compound that can potentially fight breast and lung cancer. This study explores its effects using a unique 3D cell culture technique.

Gholizadeh Siahmazgi Z et al (2023).

Cancer Cell Int.

DOI:

10.1186/s12935-023-03009-2

PubMed:

37533078

Production, bioprocessing and antiproliferative activity of camptothecin from Aspergillus terreus, endophyte of Cinnamomum camphora: restoring their biosynthesis by indigenous microbiome of C. camphora.

A. terreus endophyte of C. camphora produces high levels of camptothecin (CPT) with antimicrobial and antitumor properties. CPT yield can be restored and increased through coculturing with C. camphora microbiome. This could be a platform for industrial production of CPT.

Eldeghidy A et al (2023).

Microb Cell Fact.

DOI:

10.1186/s12934-023-02158-3

PubMed:

37533061