Cancer Studies

Dialyl-sulfide with trans-chalcone prevent breast cancer prohibiting SULT1E1 malregulations and oxidant-stress induced HIF1a-MMPs induction.

Researchers found that in specific types of breast cancer, changes in SULT1E1 and HIF1α factors can impact estrogen levels and tissue damage. Testing drug combinations targeting SULT1E1 may offer protective benefits in breast cancer treatment.

Nazmeen A, Maiti S and Maiti S (2024).
Genes Cancer.
PubMed:
39132498

Lupiwighteone as an Antitumor Agent Reverses Multidrug Resistance in K562/ADR Cells by Regulating Cellular Prion Protein-Oct4 Axis.

Researchers studied Lupiwighteone (Lup) in drug-resistant leukemia cells. Lup reversed Multidrug Resistance (MDR) in K562 cells. Potential mechanism for cancer treatment. Important for overcoming chemotherapy resistance.

Hu K et al (2024).
Anticancer Agents Med Chem.
PubMed:
39129165

Modulation of Breast Cancer Cell Apoptosis and Macrophage Polarization by Mistletoe Lectin in 2D and 3D Models.

Korean mistletoe lectin (VCA) enhances breast cancer cell apoptosis by influencing M1 and M2 macrophage polarization. Results suggest potential for VCA as an anti-cancer agent.

Hong CE and Lyu SY (2024).
Int J Mol Sci.
PubMed:
39126027

A Novel Strategy for Glioblastoma Treatment by Natural Bioactive Molecules Showed a Highly Effective Anti-Cancer Potential.

Researchers studied natural compounds, such as , , and , for treating aggressive brain tumor GBM. These compounds reduced tumor growth, migration, inflammation, and oxidative stress, offering a promising alternative to traditional treatments for better patient outcomes.

Giammona A et al (2024).
Nutrients.
PubMed:
39125270

Chitosan/Hyaluronate Complex-Coated Electrospun Poly(3-hydroxybutyrate) Materials Containing Extracts from Melissa officinalis and/or Hypericum perforatum with Various Biological Activities: Antioxidant, Antibacterial and In Vitro Anticancer Effects.

New fibrous materials were created from poly(3-hydroxybutyrate), HA, Ch, MO, and HP extracts using electrospinning. They showed high antioxidant, antibacterial, and anticancer properties, making them valuable for cancer therapy and wound dressings.

Anastasova I et al (2024).
Polymers (Basel).
PubMed:
39125132

Scutellaria barbata D.Don and Scleromitrion diffusum (Willd.) R.J.Wang inhibits the progression of triple negative breast cancer though the activation inhibition of NF-κB triggered by CAFs-derived IL6.

Researchers studied the herb pair Scutellaria barbata and Scleromitrion diffusum for their anti-tumor effects on triple-negative breast cancer. Understanding their molecular mechanisms can lead to new treatment options.

Pan Y et al (2024).
J Ethnopharmacol.
PubMed:
39121924

Deciphering Annona's Anticancer Potential: Comparative Analysis of Crude Extract Versus Nanoformulation on SCC-25 Oral Cancer Cells Through cell Viability, Apoptosis, Cell Cycle, ROS, and MMP Analysis.

Study found that Annona muricata has potential anticancer activity. Nano formulation of its extract showed promise against oral cancer cells. Important for potential cancer treatment development.

Rekha M et al (2024).
J Maxillofac Oral Surg.
PubMed:
39118929

Synergistic enhancement: Exploring the potential of piperine in cancer therapeutics through chemosensitization and combination therapies.

Piperine from black pepper shows potential in overcoming drug resistance in cancer cells by targeting key pathways and enhancing drug bioavailability. It can improve the effectiveness of chemotherapy when used with other agents.

Manickasamy MK et al (2024).
Life Sci.
PubMed:
39117139