The incidence of early-onset colorectal cancer (EOCRC) is increasing, not linked to known risk factors. Researchers hypothesize that a pharmaceutical agent may be the cause, suggesting the need for strategies to minimize this risk.
Curcumin, found in turmeric, reduces gastric cancer cell growth, migration, and invasion. It suppresses the PI3K signaling pathway, making it a potential therapeutic agent for gastric cancer. Further research is needed for in vivo effectiveness.
Bioinformatics study identifies 401 targets in cancer, MAPK signaling, and PI3K/Akt signaling pathways that Taxus chinensis (TC) binds to, potentially making it an effective treatment for lung cancer.
Scientists found that incensole acetate (IA), a compound in essential oils, has potential anticancer activity. IA biosynthesized nanoemulsion showed cytotoxicity against breast cancer cells and improved indicators in a rat model, suggesting it has anticancer properties.
Researchers identified and examined the chemosensitizing effects of Centipeda minima extracts, revealing that it inhibits FANCD2 activity. Understanding how this works could lead to improved cancer treatments.
Researchers investigated the effect of macelignan, a compound found in Myristica fragrans, on the polarization of tumor-associated macrophages in colorectal cancer metastasis. Understanding this interaction can potentially lead to new strategies for cancer treatment. (37 words)
Scientists investigated the potential of compounds in Moringa oleifera to inhibit CDK-2, a protein target in estrogen receptor-positive breast cancer. Ellagic acid, chlorogenic acid, and quercetin showed the most promise and further research is needed to validate these findings.
Researchers studied the effectiveness of plumbagin in inhibiting cell growth, tumor metastasis, and inducing apoptosis in tongue squamous cell carcinoma. Findings may lead to new therapies for this type of cancer with a poor prognosis.